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Ancient oil may keep sinus infections at bay

NCT ID NCT07198607

Prevention Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether nasal drops made from Pistacia lentiscus oil (a natural plant oil) can help prevent chronic sinusitis from coming back. 100 adults with frequent sinus infections were followed for 12 months. One group used the oil drops plus a saltwater rinse, while the other group used only the saltwater rinse. The goal was to see if the oil could reduce symptoms and improve quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Apr 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged ≥18 years with diagnosed chronic rhinosinusitis (CRS) who underwent long-term treatment with isotonic saline nasal wash plus Pistacia lentiscus oil nasal drops or isotonic saline nasal wash alone in a real-world clinical setting were retrospectively evaluated.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Clinical diagnosis of chronic rhinosinusitis * Nasal polypoid score ≤1 * ≥4 episodes of recurrence per year * SNOT-22 score ≥10 Willingness and ability to provide written informed consent Exclusion Criteria: * Nasal polypoid score \>2 * \<4 episodes of recurrence per year * SNOT-22 score \<10 * Known immune disorders * Neoplastic disorders * Neurological disorders * Psychiatric disorders * Inability to undergo treatment * Refusal or inability to provide informed consent

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic rhinosinusitis (diagnosis) Chronic rhinosinusitis without nasal polyps

Contacts and locations

Locations

  • Ent Clinic ASST Settelaghi, University of Insubriae

    Varese, Italy

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