Greek sinusitis study aims to personalize treatment by analyzing inflammation

NCT ID NCT07663409

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This study will collect and analyze nasal tissue from 230 Greek patients with chronic sinusitis (with or without nasal polyps) to identify different inflammation patterns, called endotypes. By understanding these patterns, researchers hope to better match patients with the most effective biologic treatments. The study is observational and does not test any new drug or intervention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose more personalized treatments for chronic sinusitis patients based on their specific inflammation type.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test any new therapy. Results may not apply to non-Greek populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRSWNP OR CRSSNP PATIENTS

Contacts and locations

Locations

Research Site
RECRUITING

Alexandroupoli, Greece
Research Site
NOT_YET_RECRUITING

Athens, Greece
Research Site
NOT_YET_RECRUITING

Heraklion, Greece
Research Site
NOT_YET_RECRUITING

Thessaloniki, Greece

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