New study digs into how mepolizumab changes nose bacteria and genes in asthma patients

NCT ID NCT06069310

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tracks 40 people with nasal polyps and severe asthma who are taking mepolizumab, a drug that reduces inflammation. Researchers collect nose, blood, and sputum samples before treatment and at 3, 6, and 12 months to see how the drug affects symptoms, nose bacteria, and gene activity. The goal is to find patterns that predict who responds best to treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis nasal cavity polyp pulmonary eosinophilia T2-high asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pulmonary Dept First ICU Evangelismos Hospital

    Athens, 10676, Greece

  • Pulmonary Dept First ICU, Evagelismos Hospital

    Athens, Attica, 10676, Greece