National And Kapodistrian University Of Athens

This study tests the safety of an experimental drug called anifrolumab in 20 adults with antiphospholipid syndrome (APS), a condition that raises the risk of blood clots and pregnancy complications. Participants receive weekly injections of the drug for up to 52 weeks, alongside …

This study tests whether a special software (HPI and AFM) can help anesthesiologists keep blood pressure stable during surgery. About 100 adults having general anesthesia will be randomly assigned to either standard care or care guided by the software. The goal is to see if the s…

This study compares two surgical treatments for peri-implantitis, a gum infection around dental implants. One method reshapes the implant surface (implantoplasty), while the other uses an erythritol air-abrasive device to clean it. Researchers will check which approach works bett…

This study is testing a new way to treat moderate-to-severe hemorrhoids by combining a laser procedure with a stitch technique. About 100 adults will receive the treatment and be followed for a year. The goal is to see if it reduces pain, bleeding, and tissue prolapse better than…

This study tests a procedure that uses radiofrequency heat to destroy spine tumors, followed by bone cement to stabilize the spine. Sixteen people with cancer that has spread to the spine will receive the treatment. The goal is to see if the tumors become less active on PET scans…

This early-phase trial tests whether injecting a sugar-water solution (dextrose) into acupuncture points on the back can reduce chronic low back pain better than a numbing injection alone. Sixty adults with long-term back pain will receive up to 15 injections over three sessions …

This study tests whether adding a sugar solution (dextrose) to numbing injections around the knee nerves provides better pain relief than numbing medicine alone for people with chronic knee osteoarthritis. Sixty adults with knee arthritis will receive a series of three injections…

This study looks at whether a person's genetic makeup can predict how much weight they will lose on the drugs semaglutide or tirzepatide. Researchers will follow 220 adults with obesity who are starting one of these medications for six months. By analyzing genetic risk scores and…

This study follows 100 adults who need surgery for an anal fistula. Researchers will track healing, recurrence, and quality of life for one year after the procedure. The goal is to see which surgical methods work best in real-world settings. No new treatments are being tested—onl…

This study follows 2000 people with early-stage, hormone-sensitive breast cancer to see how doctors decide on treatments, especially when using a test called EndoPredict. The goal is to track long-term outcomes like cancer return and survival over 5 to 10 years. No new treatments…

This study is for adults with a blocked radial artery who need a heart procedure like angiography or angioplasty. Doctors will use the ulnar artery in the same wrist instead. The goal is to see if this approach is safe and how it affects hand strength, feeling, and daily use. Res…

This study looks at whether a blood test marker called Monocyte Distribution Width (MDW) can help predict complications and survival in elderly patients with hip fracture. Researchers will follow 100 patients aged 65 and older, measuring MDW and other inflammatory markers at admi…

This study looks at how two weight-loss medications, tirzepatide and liraglutide, affect bone health and body composition in adults with severe obesity (BMI 40 or higher). Over 6 months, researchers will measure changes in bone turnover markers, weight, and body fat. The goal is …

This study compares two common inhaled anesthetics, sevoflurane and desflurane, in 50 adults undergoing robotic-assisted abdominal surgery. Researchers will measure airway pressure to see which drug better protects lung function. The goal is to find the safer option for patients …

This study compares five different non-surgical treatments for advanced gum disease (periodontitis) to see how they affect inflammation throughout the body and the risk of bacteria entering the bloodstream. Researchers will measure blood markers like C-reactive protein and interl…