New combo infusion aims to tame Opioid-Resistant cancer pain

NCT ID NCT07408193

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This early-phase trial tests whether combining lidocaine and ketamine can reduce severe cancer-related pain that doesn't respond to opioids. Twenty-four adults will receive two weekly infusions of the drug combination or an active placebo in a blinded, crossover design. The goal is to see if this approach provides better pain relief than placebo.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University General Hospital of Athens "Attikon" - National and Kapodistrian University of Athens Medical School

    RECRUITING

    Athens, Attica, 12461, Greece