Gum treatment showdown: which method is safest for your whole body?
NCT ID NCT07077122
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study compares five different non-surgical treatments for advanced gum disease (periodontitis) to see how they affect inflammation throughout the body and the risk of bacteria entering the bloodstream. Researchers will measure blood markers like C-reactive protein and interleukin-6 before and after treatment in 75 adults. The goal is to identify which treatment approach causes the least immediate systemic burden, helping improve safety and outcomes for patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Scaling and root planing, antibiotic prophylaxis (amoxicillin), 810nm diode laser, air polishing
- What this could lead to
- If successful, this could help dentists choose the safest gum treatment method that minimizes short-term risks like bacteria entering the bloodstream.
- What could go wrong
- This is a small, early-stage study (75 people) focused on measuring immediate effects, not long-term outcomes. Results may not apply to all patients or lead to new treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Periodontology, Dental School of Athens
RECRUITINGAthens, Greece
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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