Gum treatment showdown: which method is safest for your whole body?

NCT ID NCT07077122

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares five different non-surgical treatments for advanced gum disease (periodontitis) to see how they affect inflammation throughout the body and the risk of bacteria entering the bloodstream. Researchers will measure blood markers like C-reactive protein and interleukin-6 before and after treatment in 75 adults. The goal is to identify which treatment approach causes the least immediate systemic burden, helping improve safety and outcomes for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Scaling and root planing, antibiotic prophylaxis (amoxicillin), 810nm diode laser, air polishing

What this could lead to

If successful, this could help dentists choose the safest gum treatment method that minimizes short-term risks like bacteria entering the bloodstream.

What could go wrong

This is a small, early-stage study (75 people) focused on measuring immediate effects, not long-term outcomes. Results may not apply to all patients or lead to new treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Periodontology, Dental School of Athens

    RECRUITING

    Athens, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••