Can a probiotic tame hay fever? new study investigates
NCT ID NCT05208528
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed trial tested whether a probiotic called Bifidobacterium longum ES1, or its heat-treated version, could reduce symptoms of allergic rhinitis (hay fever) in 72 adults with moderate-to-severe dust mite allergies. Participants took daily capsules for several weeks and reported their symptoms and medication use. The goal was to see if these supplements could improve quality of life and reduce the need for rescue medicines.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bifidobacterium longum ES1 (a probiotic) and its heat-treated form (HT-ES1)
What this could lead to
If it works, this could point toward a natural supplement to help manage allergic rhinitis symptoms and reduce reliance on medication.
What could go wrong
This is a small, early-stage trial with only 72 participants. The effects may be modest or not better than a placebo, and results may not apply to everyone with allergies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Eurecat
Reus, Reus, 43204, Spain