Nose injection may ease pain after sinus surgery

NCT ID NCT02821169

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether injecting the numbing drug ropivacaine into the nose can reduce pain after endoscopic sinus surgery. 184 adults having sinus surgery were randomly given either ropivacaine or a saltwater placebo injection. The main goal was to measure pain intensity and the need for extra painkillers after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ropivacaine (a local anesthetic)

What this could lead to

If it works, this could offer a simple way to manage pain after sinus surgery without strong oral painkillers.

What could go wrong

This is a completed phase 3 trial, but the results are not yet widely known. Pain relief from a single injection may be short-lived or not better than placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU, Hôpital Claude Huriez

    Lille, France