New allergy shot shows promise for those failed by standard meds
NCT ID NCT06046391
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new drug called LP-003 in 180 adults with moderate to severe seasonal allergic rhinitis (hay fever) that wasn't well controlled by usual treatments like antihistamines or nasal sprays. LP-003 is an antibody that blocks IgE, a key driver of allergic reactions, and is designed to be stronger and last longer than existing options. Participants received either LP-003 or a placebo for 12 weeks, and researchers tracked their nasal symptoms (itching, sneezing, runny nose, congestion) using daily diaries.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Shijitan Hospital
Beijing, Beijing Municipality, 100038, China
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Changchun University of Chinese Medicine Affiliated Hospital
Changchun, Jilin, China
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Dongfang Hospital
Beijing, Beijing Municipality, China
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Linfen Peoples Hospital
Linfen, Shanxi, China
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
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Peking University Third Hospital
Beijing, Beijing Municipality, China
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Second hospital of Shanxi Medical University University
Taiyuan, Shanxi, China
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Shengjing Hospital of China Medical University
Shenyang, Liaoning, China
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The First Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
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Tianjin Peoples Hospital
Tianjing, Tianjing, China
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Tonghua central hospital
Tonghua, Jilin, China
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Xidian group hospital
Xi’an, Shanxi, China
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Yan Bian Chao Yi Hospital
Yanbian, Jilin, China
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Yanbian University hospital
Yanji, Jilin, China
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Yinchuan Peoples Hospital
Yinchuan, Ningxia, China
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Zhengzhou central hospital
Zhengzhou, Henan, China
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Zibo central hospital
Zibo, Shandong, China
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Other studies related to the condition(s) this trial covers.
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