Double-Drug attack shows promise for tough head and neck cancers
NCT ID NCT03370276
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether combining two FDA-approved cancer drugs, cetuximab and nivolumab, could help people with advanced head and neck cancer that has returned or spread. A total of 95 participants received the drug combination to find the best dose and see if it improves survival. The goal is to control the disease and extend life, not to cure it.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cetuximab and nivolumab (drug combination)
- What this could lead to
- If successful, this combination could offer a new treatment option for people with advanced head and neck cancer that has come back or spread.
- What could go wrong
- This is an early-phase trial (phase I/II), so results are preliminary. The combination may cause significant side effects and may not improve survival for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Emory University School of Medicine
Atlanta, Georgia, 30322, United States
-
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States
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The Ohio State University
Columbus, Ohio, 43210, United States
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