Which drug keeps sinus surgery cleaner? dexmedetomidine vs. nitroglycerin
NCT ID NCT07585201
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two drugs, dexmedetomidine and nitroglycerin, to see which one better reduces bleeding during functional endoscopic sinus surgery (FESS). 66 adults having elective FESS were randomly assigned to receive one of the drugs to lower blood pressure and improve the surgeon's view. The main goal was to compare surgical field quality and drug costs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine and nitroglycerin
What this could lead to
If one drug works better, it could make sinus surgeries safer and cheaper by improving visibility and reducing bleeding.
What could go wrong
This is a small, completed study with only 66 participants, so results may not apply to everyone. Both drugs have side effects like low blood pressure or slow heart rate.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Zagazig university
Zagazig, Sharqia Province, 44111, Egypt