HYPOTENSION

This study looks at how to best give hydrocortisone to newborns with low blood pressure who are being cooled for brain injury caused by lack of oxygen at birth. About 50 full-term babies will receive the drug while doctors monitor their blood pressure and drug levels. The goal is…

This study tests whether giving a drug called noradrenaline through a vein during surgery can prevent dangerously low blood pressure better than usual care. It involves 750 adults aged 45 and older having non-cardiac surgery. The goal is to see if this approach reduces episodes o…

This study compares two medicines, norepinephrine and phenylephrine, given as a steady drip to maintain blood pressure during planned C-sections under spinal anesthesia. About 140 healthy pregnant women carrying one full-term baby will take part. The goal is to see which drug wor…

This study compares two drugs, dexmedetomidine and dexamethasone, when added to a standard numbing medicine (ropivacaine) for arm surgery. The goal is to see which combination provides faster and longer pain relief. 66 adults scheduled for upper limb surgery will take part.

This study tests whether a short, guided breathing exercise done right before spinal anesthesia can help prevent dangerous drops in blood pressure and reduce anxiety in women having a planned C-section. About 150 pregnant women will be randomly assigned to either do the breathing…

This study tests a non-invasive spinal stimulation technique to help people with a recent spinal cord injury (within 30 days) manage blood pressure drops when sitting up. Participants will receive both real and sham stimulation during a sit-up test to see if it can prevent dizzin…

This study tests whether gentle electrical stimulation on the back can help people with chronic spinal cord injury maintain healthy blood pressure when they sit up. Participants will lie on a tilt table while their blood pressure is measured with and without stimulation. The goal…

This study compares two ultrasound-guided nerve blocks (S-FICB and PENG) to see which one better reduces pain when positioning patients for spinal anesthesia during femur fracture surgery. About 70 adults aged 20-70 will participate. The goal is to find the block that provides be…

This study looks at different tests doctors use to decide if giving fluids will help patients with low blood pressure and impaired consciousness. The goal is to find which tests are most accurate. About 222 adults in intensive care will take part. Results may help doctors make be…

This study looks at whether measuring skin conductance (a sign of nerve activity) can help predict sudden drops in blood pressure after spinal anesthesia in older adults with cancer. About 100 patients aged 65 and older having urologic cancer surgery will be monitored. The goal i…

This study is observing 321 pregnant women having planned C-sections to see if waist size, body mass index (BMI), and a heart rate-to-blood pressure ratio can predict a sudden drop in blood pressure after spinal anesthesia. The goal is to find better ways to identify women at ris…

This study looks at how four different blood pressure medicines (ephedrine, phenylephrine, norepinephrine, and vasopressin) affect the contractions of the womb and umbilical cord blood vessels. Researchers will take small tissue samples from 144 women having planned C-sections an…

This study looks at two common drugs used to manage blood pressure during brain surgery. The goal is to find out which one does a better job keeping blood and oxygen flowing to the brain and other organs. About 32 adults having brain tumor surgery will take part. The results will…

This study looks at 206 people having surgery to remove a pancreatic tumor. It compares standard anesthesia (general) with a combination of general and epidural anesthesia to see which causes fewer drops in blood pressure during the operation. The goal is to find the safer approa…