Massive ICU trial aims to settle debates on blood pressure, platelets, and nutrition
NCT ID NCT06605144
First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This study, called CEPEC, is a large platform trial enrolling 5,500 ICU patients across multiple countries. It tests different approaches to three common ICU treatments: how low to let blood pressure go with vasopressors, when to give platelet transfusions, and how to provide nutrition. The goal is to find out which strategies lead to better survival and recovery. By comparing treatments already used in practice, the results could directly guide doctors' decisions in the ICU.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vasopressors, platelet transfusions, and nutrition interventions
What this could lead to
If successful, this trial could help doctors make better decisions about routine ICU care, potentially improving survival and recovery for critically ill patients.
What could go wrong
This is a large, pragmatic trial, but results may not apply to all ICU patients. The interventions are already in use, so no major new risks are expected, but the study may not find clear winners among the options.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Auckland City Hospital
NOT_YET_RECRUITINGAuckland, New Zealand
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CIUSSS de l'Estrie - CHUS
RECRUITINGSherbrooke, Quebec, J1H 5N4, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre hospitalier de l'Université de Montréal (CHUM)
RECRUITINGMontreal, Quebec, H2X 0C1, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hamilton Health Sciences - Juravinski Hospital
RECRUITINGHamilton, Ontario, L8V 1C3, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Intensive Care National Audit and Research Centre (coordinating centre for sites in UK. Sites to be determined)
NOT_YET_RECRUITINGLondon, United Kingdom
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Niagara Health
RECRUITINGSt. Catharines, Ontario, L2S 0A9, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Scarborough Health Network
RECRUITINGScarborough Village, Ontario, M1P 2V5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, K1H 8L6, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••