Which drug keeps the brain safer during surgery? new study aims to find out

NCT ID NCT06083948

Recruiting now Knowledge-focused Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests two common blood-pressure-raising drugs, noradrenaline and phenylephrine, in 32 people undergoing brain tumor surgery. The goal is to see which drug better maintains blood flow and oxygen delivery to the brain and other organs. Researchers will use PET scans to measure these effects. The results may help anesthesiologists choose the best drug for future surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Noradrenaline and phenylephrine (drugs to raise blood pressure)
What this could lead to: If successful, this could help doctors choose the best drug to protect the brain and organs during surgery.
What could go wrong: This is a small, early-phase study with only 32 patients, so results may not apply to everyone. It measures blood flow, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypotensive disorder supratentorial cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOTENSION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aarhus University Hospital
RECRUITING

Aarhus, 8200, Denmark

Contact Phone: •••-•••-•••• Email: •••••@•••••

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