Asthma drug shows promise for lost smell after head trauma

NCT ID NCT07171021

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether theophylline, an asthma drug, could help people who lost their sense of smell after a head injury. 158 patients who had not improved with standard treatments took theophylline or a placebo, plus did smell training for 6 months. The goal was to see if their ability to identify and detect odors improved.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

theophylline

What this could lead to

If it works, this could point toward a treatment for smell loss after head injury.

What could go wrong

This is a small, completed Phase 4 trial. The results may not apply to everyone, and theophylline can cause side effects like nausea or heart issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anosmia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Taichung Veterans General Hospital

    Taichung, 40705, Taiwan