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New drug may help men avoid catheters after ear, nose, and throat surgery

NCT ID NCT06398899

Completed Symptom relief Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested two drugs used to reverse muscle relaxants after surgery: sugammadex and a combination of neostigmine and glycopyrrolate. The goal was to see which one better prevents urinary retention in 124 patients having ear, nose, or throat surgery who were at high risk due to prior urinary issues, enlarged prostate, or prostate cancer. The researchers wanted to find out if sugammadex causes fewer problems with urination after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sugammadex injection (Bridion) and neostigmine/glycopyrrolate injection
What this could lead to
If sugammadex works better, it could offer a safer way to reverse muscle relaxants after surgery, reducing the need for catheters in patients at risk of urinary retention.
What could go wrong
This is a small, completed study with 124 patients, so results may not apply to everyone. The benefit over standard care may be modest, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia chronic otitis media chronic rhinosinusitis laryngeal disorder prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC OTITIS MEDIA CHRONIC SINUSITIS HEAD AND NECK SURGERY LARYNGEAL DISEASE

Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

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