New drug may help men avoid catheters after ear, nose, and throat surgery
NCT ID NCT06398899
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested two drugs used to reverse muscle relaxants after surgery: sugammadex and a combination of neostigmine and glycopyrrolate. The goal was to see which one better prevents urinary retention in 124 patients having ear, nose, or throat surgery who were at high risk due to prior urinary issues, enlarged prostate, or prostate cancer. The researchers wanted to find out if sugammadex causes fewer problems with urination after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sugammadex injection (Bridion) and neostigmine/glycopyrrolate injection
What this could lead to
If sugammadex works better, it could offer a safer way to reverse muscle relaxants after surgery, reducing the need for catheters in patients at risk of urinary retention.
What could go wrong
This is a small, completed study with 124 patients, so results may not apply to everyone. The benefit over standard care may be modest, and individual responses can vary.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Taiwan University Hospital
Taipei, 100, Taiwan