Nasal spray could shrink polyps and reduce need for surgery

NCT ID NCT07675512

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether a nasal spray containing adelmidrol can reduce inflammation and shrink nasal polyps in people with chronic sinusitis. Participants are adults aged 18 to 70 who are scheduled for sinus surgery. Half receive standard care plus the adelmidrol spray, while the other half receive standard care alone. The study measures polyp size, symptoms, and whether the spray improves recovery after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
adelmidrol nasal spray
What this could lead to
If it works, this could offer a new way to control nasal polyps and reduce the need for surgery in some patients.
What could go wrong
This is a small, early-stage study. The results may not apply to everyone, and the spray may not work better than standard treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ospedale di Fano, Dipartimento di Otorinolaringoiatria

    Fano, Italy