Can kids with allergies use nasal spray only when needed? new study investigates.

NCT ID NCT05299086

Completed Symptom relief Sponsor: Mahidol University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether children with year-round allergic rhinitis can use a nasal steroid spray only when symptoms bother them, instead of every day. Sixty-eight children aged 6 to 18 were randomly assigned to either daily use or as-needed use of fluticasone furoate spray. The goal was to compare how well each approach controls nasal symptoms like sneezing, itching, runny nose, and congestion, and to see if as-needed use reduces side effects and total drug exposure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fluticasone furoate nasal spray
What this could lead to: If it works, this could show that using the spray only when symptoms flare is just as effective as daily use, with fewer side effects and lower total drug exposure.
What could go wrong: This is a small, completed Phase 3 trial with only 68 children, so results may not apply to all kids. The as-needed approach might not control symptoms as well in more severe cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

CHILD syndrome perennial allergic rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILD, ONLY PERENNIAL ALLERGIC RHINITIS

Contacts and locations

Locations

Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok, Bangkok, 10700, Thailand

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