Heart valve disorder

This trial investigates whether a minimally invasive procedure called mitral valve TEER, added to standard medical therapy, improves outcomes for heart failure patients whose mitral valve leakage becomes severe only during exercise. Participants are randomly assigned to receive e…

This trial is testing a new device called MRace to repair a leaky mitral valve in people with severe functional mitral regurgitation, a condition where the valve doesn't close properly, causing blood to flow backward. The device is placed through a vein in the leg and guided to t…

This study tests a new device called MRace, designed to repair severe mitral regurgitation—a condition where the heart's mitral valve doesn't close properly, causing blood to leak backward. The device is implanted through a vein in the leg, avoiding open-heart surgery, and is aim…

This study tests a new device called MRace, designed to repair a leaky mitral valve in the heart without open surgery. The device is placed through a vein in the leg and guided to the heart to help the valve close properly. The trial will include up to 15 people with severe mitra…

This trial tests whether repairing a leaky mitral valve early, using a minimally invasive clip procedure, can help people with heart failure and reduced pumping function tolerate and benefit from standard heart failure medications. Participants are randomly assigned to receive th…

This study follows people with moderate to severe pulmonary regurgitation or stenosis who receive the PULSTA transcatheter pulmonary valve, a less invasive option for replacing a faulty heart valve. Researchers will track how well the valve works over time, measuring improvements…

This trial is testing whether a new heart valve device, called Myval, can safely and effectively treat people with severe aortic regurgitation—a condition where the heart's aortic valve doesn't close properly, causing blood to leak backward. The study involves about 164 adults wh…

This trial compares two methods for closing the main artery in the leg after a TAVI procedure, which replaces a heart valve without open surgery. Half of the participants will have the artery closed with a single suture device, while the other half will receive a hybrid approach …

This study tests a device called TricValve for people with severe tricuspid regurgitation, a condition where a heart valve leaks. The device is implanted in the veins to help blood flow better. About 780 participants will be randomly assigned to get the device plus standard medic…

This trial tests whether a catheter-based procedure called transcatheter edge-to-edge repair (TEER) can improve outcomes in people with atrial functional mitral regurgitation, a condition where the heart's left atrium enlarges and causes the mitral valve to leak. The study will e…

This trial asks whether people with severe aortic stenosis can safely go home the same day after a minimally invasive heart valve replacement (TAVI) instead of staying in the hospital. About 764 patients who are stable six hours after the procedure will be randomly assigned to ei…

This trial tests whether wearing a portable heart monitor for two weeks after a TAVI procedure can reduce the risk of sudden death, dangerous heart rhythms, or stroke within the following year. People who have had a successful TAVI and show certain electrical abnormalities on the…

This trial tests whether angiotensin receptor blockers (ARBs), a type of blood pressure medication, can reduce the risk of death or heart failure in people who have had a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis and still have a thickened heart mus…

This trial is testing a new device called the Crea Aortic Valve, a replacement heart valve that can be implanted through a catheter without open-heart surgery. It is designed for people aged 60 and older with severe aortic stenosis—a narrowing of the heart's main valve—who are co…

This pilot study is testing whether a smartphone app called HeartMate can help people with heart disease manage their condition from home. Over six weeks, participants use the app for daily heart checks, guided exercise, breathing training, and a mind program, with weekly coachin…

This study tests a new device called the Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System for people with severe tricuspid regurgitation, a condition where the heart's tricuspid valve leaks blood backward. The device is placed through a catheter, avoiding open-hear…

This study tests whether the drug vericiguat can slow the buildup of calcium on the aortic valve in people with mild-to-moderate aortic valve stenosis. Participants take vericiguat or a placebo daily for 24 months, with regular heart scans to track valve calcium and function. The…

This trial tests whether adding a 3D holographic visualization tool, called EchoPixel Holographic Therapy Guidance, helps doctors perform two common heart procedures more accurately. The procedures are left atrial appendage occlusion (for atrial fibrillation) and mitral valve rep…

This study tests whether two heart failure medications, dapagliflozin and spironolactone, can help the heart recover better after aortic valve replacement. About 445 adults with severe aortic stenosis will take one or both drugs daily for 12 months. The goal is to see if these me…

This clinical trial is testing a new heart valve replacement system called Encantor, which uses software to guide placement of the valve. The study includes 150 adults with severe aortic stenosis who are candidates for a minimally invasive procedure. Researchers will track how ma…

This trial tests whether a newer balloon-expandable heart valve with intermediate sizes (Myval) is as safe as a standard self-expanding valve (Evolut) in people with severe aortic stenosis whose valve measurements fall in a 'borderline' range. About 600 participants will be rando…

This study is testing a new artificial heart valve, called the TRIFORMIS RESILIA, for people who need their tricuspid valve replaced. The tricuspid valve controls blood flow between two right heart chambers. Researchers will follow 75 adults who receive this valve during surgery …

This early trial tests a new device called Anchord that repairs leaky mitral valves without open-heart surgery. It will include 5 people with severe valve leakage who are too high-risk for standard surgery. The goal is to see if the device is safe and can reduce the leak, improvi…

This pilot study tests whether heart failure patients whose heart function has returned to normal can safely stop taking two medications (sacubitril/valsartan and dapagliflozin or empagliflozin). Eighty adults whose heart failure was caused by a treatable condition like a heart v…

This study tests whether the drug vericiguat can improve right heart function and reduce tricuspid regurgitation in 100 adults with heart failure and reduced pumping ability. Participants take vericiguat daily for 9 months, with regular heart scans and walking tests to measure ef…

This study tests a new device called the X-Clip, which is used to repair a leaky mitral valve without open-heart surgery. The device is inserted through a blood vessel and clips the valve to help it close better. The trial will include 15 adults with moderate-to-severe or severe …

This study looks at a device called ShortCut that splits old heart valve leaflets before placing a new valve inside it. The goal is to keep the arteries open and prevent blockages. About 150 people with aortic stenosis who are at risk for this complication will take part. Researc…

This study will test if taking oral azithromycin pills for three days each month works as well as getting a monthly penicillin shot to prevent rheumatic heart disease from getting worse. The trial plans to enroll 474 Nigerian secondary school students aged 10-18 with mild or mode…

This study tests a step-by-step treatment plan for people with a narrowed aortic valve who also have leaky mitral or tricuspid valves. After a minimally invasive procedure to fix the aortic valve, doctors will check if the other valves still leak badly. If so, additional procedur…

This study looks at whether a common heart valve procedure called TAVI is safe when done in hospitals that don't have heart surgery available on-site. About 600 people with severe aortic stenosis will be randomly assigned to have TAVI either with or without surgical backup. The g…

This study tests whether valsartan, a common blood pressure drug, can slow the worsening of atrial functional mitral regurgitation (a leaky heart valve) in 50 adults with normal heart pumping function. Participants take either valsartan or a placebo twice daily for 12 months, wit…

This study tests whether the drug finerenone can help people with heart failure who have had a heart valve replacement (TAVI). About 2,800 older adults will be randomly assigned to receive finerenone or a placebo. The goal is to see if the drug lowers the chance of death or worse…

This study looks at how safe and effective the SAPIEN 3 heart valve is for people with a certain type of bicuspid aortic valve stenosis (Type-0). About 170 people in China will be observed after the procedure to track serious problems like death, stroke, or rehospitalization. The…

This study tests whether creating a small opening between the upper heart chambers during mitral valve repair can prevent heart failure symptoms after surgery. Researchers will compare 50 patients who get the extra opening to those who have standard surgery alone. The goal is to …

This study compares a new heart valve implant (Myval) to standard medication in 778 people aged 65+ with moderate aortic stenosis. The goal is to see if the implant reduces death, stroke, heart failure, and improves quality of life over 2 years. Participants will be randomly assi…

This study tests a new device called the TRiCares Topaz, which replaces the tricuspid heart valve without open surgery. It is for people with severe tricuspid regurgitation (a leaky valve) who still have symptoms despite medication. The study will compare this device to another a…

This registry follows 1,000 adults with mitral regurgitation who receive the MitraClip G5, a device that repairs the heart valve without open-heart surgery. Researchers will measure how well the procedure reduces valve leakage and improves symptoms like shortness of breath. All d…

This trial compares two latest-generation heart valves (SAPIEN 3 Ultra Resilia and Evolut FX) in 200 patients with severe aortic stenosis. Participants will be randomly assigned to receive one valve during a standard procedure and followed for one year. The goal is to see which v…

This study tests whether using only ultrasound (echocardiography) to guide a minimally invasive heart valve replacement is as effective as the standard method that combines X-ray and ultrasound. The goal is to reduce kidney injury from contrast dye and lower radiation exposure. A…

This early study tests a new device called the TRICENTO G2 to treat severe tricuspid regurgitation, a condition where a heart valve leaks badly. Ten adults with symptoms like shortness of breath or swelling will get the valve through a minimally invasive procedure. The goal is to…

This registry will follow 200 people with severe aortic valve stenosis who receive a non-invasive ultrasound therapy called Valvosoft. The treatment uses focused sound waves to soften calcium buildup on the valve without surgery. Researchers will track safety and effectiveness fo…

This study tests whether a smartphone app powered by artificial intelligence can help adults recover after heart surgery. 500 patients will either use the app plus standard care or standard care alone. The app gives personalized advice on medications, spotting complications early…

This trial is for people whose surgically implanted aortic heart valve has stopped working properly. It compares two types of replacement valves placed through a tube in the leg (TAVI): a newer self-expanding valve (Hydra) versus standard balloon-expandable valves (Sapien or MyVa…

This early study tests a device called the MRace implant to treat moderate-to-severe mitral regurgitation, a condition where the heart valve leaks. About 15 people will get the implant and be followed for up to 5 years to see if it safely reduces the leak and improves symptoms. T…

This study looks at whether a common heart valve replacement (TAVI) can be performed safely in hospitals that do not have a cardiac surgery team on-site. Currently, TAVI is only done in hospitals with heart surgery backup, which can cause long wait times. The trial will randomly …

This study tests whether a drug called a PCSK9 inhibitor (Tafolecimab) can slow the progression of mild to moderate calcific aortic stenosis, a condition where the heart valve narrows and hardens. Researchers will give the drug to half of 160 participants and compare changes in v…

This study follows about 300 patients across Europe who need a second minimally invasive heart valve replacement (TAVI-in-TAVI) because their first valve has worn out or is leaking. Doctors will use the Myval valve for the replacement. The study will track how well the procedure …

This study tests whether a daily low-dose anti-inflammatory drug (colchicine) can prevent blood clots from forming on replacement heart valves after a minimally invasive valve procedure (TAVR). About 116 people who have had TAVR will either receive colchicine plus standard care o…

This early study tests a new device that fixes a leaky mitral valve without open-heart surgery. It is for people with severe symptoms who are too high-risk for traditional surgery. Only 5 participants will be enrolled to check if the device is safe and works as intended.

This study tests whether setting a pacemaker to a faster rate (90 beats per minute) can help people with right heart failure and severe tricuspid regurgitation. Twenty-four participants with a low resting heart rate will get a special pacemaker implant and be followed for 6 month…

This study tests a new way to replace a leaky heart valve (aortic regurgitation) without using X-rays or contrast dye, which can harm the kidneys. Instead, doctors will use only ultrasound (echocardiography) to guide the procedure. The goal is to see if this approach is safe and …

This study tests a new device called the J-Valve Transfemoral System in 50 adults who have a heart pump (LVAD) and a severely leaking aortic valve. The valve is replaced through a blood vessel, avoiding open-heart surgery. The goal is to see if it safely stops the leak and improv…

This study tests a new way to replace the aortic valve in people with a leaky heart valve (aortic regurgitation) without using X-rays or contrast dye. Instead, doctors will rely on ultrasound (TEE) to guide the procedure. The goal is to see if this approach is safe and effective,…

This study will test whether giving an extra antibiotic during a heart valve replacement procedure (TAVI) can lower the chance of bloodstream infection or death within 6 months. About 2,000 patients in Denmark will take part. Half will get the standard antibiotic, and half will g…

This study tests whether adding adenosine to the standard heart-protecting solution used during bypass surgery helps the heart recover better. Sixty adults having elective valve or bypass surgery will receive either adenosine or a placebo. Researchers will measure heart function,…

This study compares two blood thinners, apixaban and warfarin, in 120 adults with atrial fibrillation who recently had heart valve repair or replacement. The goal is to see if apixaban causes fewer major bleeding events while still preventing blood clots. Participants will be fol…

This study tests whether adding a second balloon inflation (called 'double tap') after placing a new heart valve improves how well the valve opens and works. About 250 adults with severe aortic stenosis getting a TAVI procedure will be randomly assigned to receive the standard pr…

This study follows 110 patients who had mitral valve repair surgery using the Chord-X system to see how well the device holds up over 10 years. Researchers will check for return of moderate-to-severe mitral regurgitation and other safety issues. Participants agree to share their …

This trial tests a procedure called TEER, which uses a clip to repair a leaky heart valve (mitral regurgitation) caused by an irregular heartbeat (atrial fibrillation). The study will include 400 people with moderate-to-severe or severe leakage who still have symptoms despite tak…

This registry will follow 150 people with severe mitral regurgitation who receive the HighLife transcatheter mitral valve replacement system. The goal is to see how well the device works and how safe it is when used in everyday medical practice. Participants are treated according…

This study tests a new device called the TAVR Assist System, which helps doctors perform a heart valve replacement procedure (TAVR) for severe aortic stenosis. The trial will compare the assist system to the standard manual TAVR in 158 older adults. The goal is to see if the devi…

This registry will follow 500 adults who need surgical replacement of their aortic or mitral heart valve with a Dafodil bioprosthetic valve. The study collects real-world data on survival, valve function, and complications like blood clots or infection over 5 years. It aims to he…

This study looks at people with atrial fibrillation (an irregular heartbeat) who have already had a successful mitral valve repair. It compares two approaches: catheter ablation (a procedure to fix the heart's electrical signals) versus standard medical care. The goal is to see i…

This study will enroll 404 people with severe leakage in both the mitral and tricuspid heart valves. Participants will be randomly assigned to have either both valves repaired at once using a catheter-based device, or only the mitral valve repaired. The goal is to see which appro…

This trial tests a new device called the ArcFlex Sheath, a bendable tube used during TAVR surgery to replace a faulty aortic valve. The goal is to see if it helps doctors position the new valve more easily and safely compared to a standard sheath. About 180 people who need TAVR s…

This study tests a new heart valve (SAPIEN X4) in 125 people with mitral valve disease who are too high-risk for open-heart surgery. The valve is placed using a thin tube through a blood vessel, avoiding major surgery. The goal is to see if the valve is safe and improves heart fu…

This study tests a device called CA330 that filters blood during heart surgery to reduce severe bleeding. It includes 120 adults on blood thinners who need non-elective heart surgery. Participants are randomly assigned to receive either the filter plus standard care or standard c…

This study tests a new device called the MIA-T system, which is inserted through a catheter to repair the tricuspid valve in people with severe leakage. The trial will enroll 600 patients who are too high-risk for traditional surgery. The goal is to see if the device safely impro…

This study tests a new device called DragonFly M2 to repair leaky mitral valves in people with moderate-to-severe or severe mitral regurgitation who are at high risk for surgery. The device is inserted through a blood vessel, avoiding open-heart surgery. The study will check if t…

This study tests whether giving a single dose of intravenous iron the day after heart surgery can reduce the chance of long-term anemia. About 180 adults with low iron or anemia before surgery will be randomly assigned to receive either the iron treatment or a placebo. The main g…

This study tests a device called DragonFly that clips a leaky mitral valve shut, helping blood flow properly in people with heart failure. About 148 adults with moderate-to-severe or severe functional mitral regurgitation who still have symptoms despite medication will be randoml…

This study tests whether a minimally invasive heart valve repair procedure (TEER) plus standard medication can reduce hospital readmissions over two years in people with moderate mitral regurgitation that worsens with exertion. About 300 participants will be randomly assigned to …

This study will test whether adding a special breathing exercise (inspiratory muscle training) to standard cardiac rehab helps heart patients recover better. About 80 adults who have been hospitalized for a heart condition will take part. The main goal is to see if the training i…

This study tests a new device called the HighLife TSMVR system for people with severe mitral regurgitation, a condition where the heart's mitral valve leaks. The device is placed through a catheter via a vein, avoiding open-heart surgery. The trial will include 240 participants w…

This early study tests a tele-operated robot called TAVIPILOT that helps doctors position a new heart valve during a minimally invasive procedure called TAVR. Ten patients aged 65 and older with severe aortic stenosis will take part. The main goals are to see if the robot is safe…

This trial tests whether an AI-guided handheld ultrasound, used during routine primary care or geriatrics visits, can detect serious heart valve disease and weak heart muscle in adults aged 65 to 85 who have no known heart problems. Half of the participants will receive this quic…

This study aims to see if a new method using electrical and mechanical signals from the heart can accurately diagnose valvular heart disease. Researchers will recruit 1,300 adults with and without valve problems to compare the new test against standard echocardiography. If it wor…

This study will enroll 5000 adults to see if a one-minute, single-lead ECG, analyzed by machine learning, can detect heart conditions like high blood pressure, heart failure, and diabetes. Participants will have their ECG recorded twice and compared with full medical exams. The g…

This study is testing a new digital stethoscope that listens for subtle changes in heart sounds to detect coronary artery disease and valve problems earlier. Researchers will record heart sounds from 500 adults who are already scheduled for heart scans or echocardiograms. The goa…

This study compares two ways to diagnose bleeding problems during surgery: a quick bedside test (viscoelastic test) and standard lab tests. The goal is to see which method gives faster results, helping doctors treat bleeding sooner. About 210 adults having high-risk surgeries (li…

This study tests whether placing soft foam dressings on the skin before heart surgery can prevent pressure injuries (bedsores). About 80 adults having long heart surgeries will be enrolled. Researchers will check for new skin injuries after surgery and track how severe they are. …

This trial tests whether two heart medications, metoprolol and amiodarone, can prevent new-onset atrial fibrillation (AFib) in people who develop minor rhythm issues after transcatheter aortic valve replacement (TAVR). About 198 participants will be randomly assigned to one of th…

This study tests whether closing the left atrial appendage (a small pouch in the heart) during valve surgery can prevent silent brain injuries in 100 adults without atrial fibrillation. Participants will have brain scans after surgery to check for hidden strokes. The goal is to f…

This study tests whether injecting a local anesthetic near the stellate ganglion in the neck, guided by ultrasound, can improve how patients feel after heart surgery. The block temporarily calms part of the nervous system, which may reduce pain, improve sleep, and lower the risk …

This study tests whether foot massage or kinesio taping can help older adults (65+) move better and feel less afraid of movement after heart surgery. Sixty participants will receive one of the two treatments daily for a week. Researchers will measure mobility, pain, and fear of m…

This study tests whether giving a special fluid (colloid) before anesthesia can prevent blood pressure drops in 116 people undergoing transcatheter aortic valve replacement (TAVR). Participants will receive either the colloid or a standard salt solution before anesthesia. The goa…

This study tests whether the TriClip device, which repairs a leaky tricuspid valve without open surgery, can improve daily life for people with severe tricuspid regurgitation. 150 participants will be randomly assigned to receive either the TriClip or a placebo procedure. The mai…

This study compares two sedatives, remimazolam and midazolam, to see which one causes less confusion (delirium) after heart valve surgery in people aged 65 and older. Delirium affects up to 70% of older heart surgery patients and can lead to longer hospital stays and memory probl…

This study compares two types of heart valve surgery: a newer, less invasive method through a small cut on the right side of the chest versus the traditional method through a cut down the middle of the chest. Researchers will measure how quickly patients recover, including time o…

This study tracks 100 people in the UK who are getting a TAVI procedure to replace a narrowed heart valve. Researchers will measure how the procedure affects their quality of life, mental health, and thinking skills over one year. The goal is to understand the real-world benefits…

This study tests a personalized, digitally supported prehabilitation program for adults waiting for elective cardiac surgery. Participants receive education, psychosocial support, nutritional advice, and home-based exercise guidance during the routine 6-10 week preoperative perio…

This study tests whether wearable devices and artificial intelligence can help personalize the timing of valve replacement in people with moderate to severe aortic stenosis who have no symptoms. Participants wear a smartwatch to track heart rate, activity, and blood pressure, and…

This study will create a computer tool to predict which older adults are at high risk for serious problems after heart or blood vessel surgery. It will also test if special programs before and during surgery can help prevent confusion, heart issues, and death. About 1,200 people …

This study will compare two newer pacemaker technologies—left bundle branch area pacing and leadless pacing—to see how they affect heart function and the tricuspid valve. Twenty adults with certain heart block conditions will receive both types temporarily during their routine pa…

This study will examine how the heart-lung machine used during cardiac surgery changes platelet function and metabolism. Researchers will take blood samples from 100 adult heart surgery patients at several time points. The goal is to link these platelet changes to post-surgery in…

This study will follow 500 people with severe aortic stenosis who need a heart valve replacement. Researchers want to see if a dedicated Heart Valve Unit—a team of heart specialists working together—can reduce confusion, delirium, and memory problems that sometimes happen after t…

This study will compare two common types of heart valves used in TAVI (a procedure to replace a narrowed aortic valve) to see which one sends fewer tiny particles to the brain during the procedure. 80 adults with severe aortic stenosis will be randomly assigned to receive either …

This study will follow 5,500 people in China who receive new heart valve devices (replacement or repair) for conditions like aortic stenosis or mitral regurgitation. Researchers will track safety issues such as stroke, bleeding, and device function over time. The goal is to see h…

This study will test a new ultrasound catheter called VeriSight Pro that takes pictures from inside the heart. Doctors will use it during procedures like closing a hole in the heart or fixing a valve. The goal is to see if it helps guide these procedures safely and effectively. A…

This observational study will follow 50 people with severe tricuspid regurgitation (a leaky heart valve) and reduced heart function who undergo valve repair using the PASCAL Precision System. The main goal is to see if, 12 months after repair, patients can take higher doses of st…

This study observes 600 people with aortic stenosis who cannot have a standard TAVI procedure through the leg artery. Instead, doctors will use other access points, like the chest or neck, to replace the heart valve. The goal is to track safety and success rates of these alternat…

This study looks at whether advanced heart pressure wave analysis can predict how well patients recover after a TAVR procedure for severe aortic stenosis. Researchers will measure pressure waves during the procedure and track quality of life and heart complications over one year …

This study tests a special catheter that measures how well the right side of the heart is working in 8 people with severe tricuspid regurgitation (a leaky heart valve). Participants are already scheduled for a procedure to fix the valve. The goal is to see if this tool can help d…

This study will create a registry of about 120 patients in Poland who have carcinoid heart disease, a rare complication of neuroendocrine tumors that damages heart valves. Researchers will collect medical records, echocardiograms, and lab results to better understand who develops…

This study will implant a small heart monitor under the skin of 100 people with moderate-to-severe mitral valve regurgitation who have few or no symptoms. The device will track heart rhythms for up to three years to find hidden atrial fibrillation that standard tests might miss. …

This study will observe 143 older adults with severe aortic stenosis who are scheduled for a minimally invasive valve replacement procedure called TAVR. Researchers want to find out how many also have cardiac amyloidosis, a condition where abnormal proteins build up in the heart.…

This pilot study will follow 90 men aged 18-50 who need heart surgery, some of whom will take the blood thinner warfarin afterward. Researchers will track changes in sperm count, movement, shape, DNA health, and hormone levels over 12 months. The goal is to see if warfarin harms …

This study will collect information from 15 patients in Asia-Pacific who have had or will have a less invasive procedure to fix a failed mitral or tricuspid heart valve. The goal is to learn how well these procedures work in this population, since most existing data comes from We…

This study will measure a specific heart function index in 2,640 healthy adults and people with heart conditions using AI-enhanced 3D ultrasound. The goal is to establish normal ranges and see how this measurement changes in diseases like heart failure and high blood pressure in …

This study aims to create an artificial intelligence (AI) model that analyzes ultrasound videos of the heart to help doctors decide if a patient with a leaky mitral valve (mitral regurgitation) is a good candidate for a minimally invasive repair procedure called TEER. The researc…

This study will follow 6,000 people in China who have both coronary heart disease and a leaky heart valve (ischemic mitral regurgitation). Researchers will collect medical data and track outcomes like hospitalizations and deaths over two years. The goal is to understand the disea…

This study compares two established techniques for placing a TAVI heart valve to see which one better aligns the valve with the patient's own valve openings, reducing the risk of blocking coronary arteries. Forty patients with severe aortic stenosis will be randomly assigned to o…

This study will compare two ways of measuring pressure inside the heart during heart surgery: the gold standard (direct left atrial pressure) and a more common indirect method (pulmonary capillary wedge pressure). Researchers want to see if the indirect method is accurate enough …

This study will compare how well heart and lung function recover after robot-assisted heart surgery versus traditional open-heart surgery. Researchers will measure exercise capacity and breathing in 80 patients before and after surgery. The goal is to see if the less invasive rob…

This study looks at 300 people with severe mitral regurgitation who need heart surgery. Researchers want to see if a special ultrasound technique called speckle tracking can better predict who will do well after surgery, compared to the current standard method. The study only use…