New heart valve clip shows promise in early trial
NCT ID NCT07660185
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new device called the X-Clip, which is used to repair a leaky mitral valve without open-heart surgery. The device is inserted through a blood vessel and clips the valve to help it close better. The trial will include 15 adults with moderate-to-severe or severe mitral regurgitation. Researchers will check for serious side effects within 30 days and see if the valve repair holds up at 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- X-Clip Mitral Valve Clip System (a device implanted via a catheter to repair the mitral valve)
- What this could lead to
- If successful, this could offer a less invasive treatment option for people with a leaky mitral valve, potentially avoiding open-heart surgery.
- What could go wrong
- This is a very small early study (15 people) testing safety and performance. The device may not work as well in a European population, and risks include serious bleeding, stroke, or need for repeat procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TRANSCATHETER MITRAL VALVE REPAIR OF DEGENERATIVE MITRAL REGURGITATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Complejo Hospitalario Universitario de Vigo
Vigo, 36312, Spain
-
Hospital Clinic de Barcelona
Barcelona, 08036, Spain
-
Hospital Universitario de Salamanca
Salamanca, 37007, Spain