New heart valve clip shows promise in early trial

NCT ID NCT07660185

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new device called the X-Clip, which is used to repair a leaky mitral valve without open-heart surgery. The device is inserted through a blood vessel and clips the valve to help it close better. The trial will include 15 adults with moderate-to-severe or severe mitral regurgitation. Researchers will check for serious side effects within 30 days and see if the valve repair holds up at 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

X-Clip Mitral Valve Clip System (a device implanted via a catheter to repair the mitral valve)

What this could lead to

If successful, this could offer a less invasive treatment option for people with a leaky mitral valve, potentially avoiding open-heart surgery.

What could go wrong

This is a very small early study (15 people) testing safety and performance. The device may not work as well in a European population, and risks include serious bleeding, stroke, or need for repeat procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Complejo Hospitalario Universitario de Vigo

    Vigo, 36312, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario de Salamanca

    Salamanca, 37007, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••