New heart valve clip aims to ease breathing and cut hospital visits
NCT ID NCT07243158
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a device called DragonFly that clips a leaky mitral valve shut, helping blood flow properly in people with heart failure. About 148 adults with moderate-to-severe or severe functional mitral regurgitation who still have symptoms despite medication will be randomly assigned to get the clip or continue standard drug therapy. The goal is to see if the clip improves survival, reduces hospitalizations for heart failure, and eases symptoms like shortness of breath.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- DragonFly transcatheter mitral valve clip system (a device implanted via a catheter to repair the mitral valve)
- What this could lead to
- If successful, this could offer a less invasive treatment option for people with functional mitral regurgitation who remain symptomatic despite medication, potentially reducing heart failure hospitalizations and improving quality of life.
- What could go wrong
- This is an early-stage study with only 148 participants, so results may not apply to everyone. The procedure carries risks like bleeding, infection, or the clip not working as expected, and long-term benefits are not yet proven.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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