New valve procedure aims to fix leaky heart in pump patients

NCT ID NCT07363473

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new device called the J-Valve Transfemoral System in 50 adults who have a heart pump (LVAD) and a severely leaking aortic valve. The valve is replaced through a blood vessel, avoiding open-heart surgery. The goal is to see if it safely stops the leak and improves heart function and survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

J-Valve Transfemoral System (a replacement heart valve delivered through a blood vessel)

What this could lead to

If it works, this could offer a less invasive way to fix a leaking aortic valve in people who already have a heart pump, potentially improving their heart function and quality of life.

What could go wrong

This is an early study with only 50 participants, so results may not apply to everyone. Risks include valve movement, need for a second valve, or death.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve disorder aortic valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••