AORTIC INSUFFICIENCY
Clinical trials for AORTIC INSUFFICIENCY explained in plain language.
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New heart valve procedure could offer safer alternative to Open-Heart surgery for seniors
Disease control Recruiting nowThis study tests whether a newer, less invasive procedure called transcatheter aortic valve replacement (TAVR) using the J-VALVE device is as safe and effective as traditional open-heart surgery for people with severe aortic regurgitation (a leaky heart valve). About 1,250 adults…
Matched conditions: AORTIC INSUFFICIENCY
Phase: NA • Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New heart valve under 10-Year watch: will it last?
Disease control Recruiting nowThis registry will follow 500 adults with severe aortic stenosis who receive a SAPIEN 3 Ultra Resilia heart valve through a minimally invasive procedure. Researchers will track how well the valve works and how safe it is over 10 years. The goal is to see if this newer valve desig…
Matched conditions: AORTIC INSUFFICIENCY
Sponsor: Institut für Pharmakologie und Präventive Medizin • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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New heart valve procedure could offer a gentler option for leaky valve patients
Disease control Recruiting nowThis study tests a new, less invasive way to replace a leaky aortic heart valve (aortic regurgitation) using a device called the JenaValve Trilogy, compared to standard open-heart surgery. About 1,000 people with moderate to severe aortic regurgitation will be randomly assigned t…
Matched conditions: AORTIC INSUFFICIENCY
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New registry to monitor Long-Term success of keyhole heart valve treatments
Knowledge-focused Recruiting nowThis study is a registry that collects information from routine care to see how well minimally invasive heart valve procedures work over 5 years. It includes adults over 18 who have had a transcatheter aortic valve replacement or similar treatment. No new treatments are given; th…
Matched conditions: AORTIC INSUFFICIENCY
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC