AORTIC INSUFFICIENCY
Clinical trials for AORTIC INSUFFICIENCY explained in plain language.
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New heart valve procedure could offer a gentler option for leaky valve patients
Disease control Recruiting nowThis study tests a new, less invasive way to replace a leaky aortic heart valve (aortic regurgitation) using a device called the JenaValve Trilogy, compared to standard open-heart surgery. About 1,000 people with moderate to severe aortic regurgitation will be randomly assigned t…
Matched conditions: AORTIC INSUFFICIENCY
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New heart valve device could help patients with heart pumps avoid open surgery
Disease control Recruiting nowThis study is testing a new heart valve device (JenaValve Trilogy) placed through a tube in an artery, without open surgery. It is for 50 adults who have a mechanical heart pump (LVAD) and also a leaky aortic valve that makes the pump work less effectively. The goal is to see if …
Matched conditions: AORTIC INSUFFICIENCY
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New heart valve procedure could offer safer alternative to Open-Heart surgery for seniors
Disease control Recruiting nowThis study tests whether a newer, less invasive procedure called transcatheter aortic valve replacement (TAVR) using the J-VALVE device is as safe and effective as traditional open-heart surgery for people with severe aortic regurgitation (a leaky heart valve). About 1,250 adults…
Matched conditions: AORTIC INSUFFICIENCY
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New registry to monitor Long-Term success of keyhole heart valve treatments
Knowledge-focused Recruiting nowThis study is a registry that collects information from routine care to see how well minimally invasive heart valve procedures work over 5 years. It includes adults over 18 who have had a transcatheter aortic valve replacement or similar treatment. No new treatments are given; th…
Matched conditions: AORTIC INSUFFICIENCY
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC