Heart drugs tested to stop AFib after TAVR

NCT ID NCT07519161

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether two heart medications, metoprolol and amiodarone, can prevent new-onset atrial fibrillation (AFib) in people who develop minor rhythm issues after transcatheter aortic valve replacement (TAVR). About 198 participants will be randomly assigned to one of the drugs or to observation only. The study will track who develops AFib over 90 days and monitor for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Metoprolol succinate and amiodarone
What this could lead to
If successful, this could provide a clear drug strategy to prevent atrial fibrillation after TAVR, reducing stroke and hospitalization risk.
What could go wrong
This is a relatively small, early-stage trial (198 people) with no phase designation. Both drugs have known side effects, and the results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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