Heart valve positioning study aims to prevent artery blockage

NCT ID NCT07217691

Not yet recruiting Knowledge-focused Sponsor: Oslo University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two established techniques for placing a TAVI heart valve to see which one better aligns the valve with the patient's own valve openings, reducing the risk of blocking coronary arteries. Forty patients with severe aortic stenosis will be randomly assigned to one of the two methods. After the procedure, a CT scan checks the valve's position. The goal is to identify a technique that could become the new standard, improving safety and outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Evolut FX+ transcatheter aortic valve implantation device
What this could lead to: If one technique proves better, it could become the new standard for TAVI procedures, improving patient safety and reducing coronary blockage risks.
What could go wrong: This is a small, early-stage study (40 participants) comparing two already-used techniques. It may not show a clear difference, and results may not apply to all patients or valve types.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis commissural facial cleft

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC STENOSIS COMMISSURAL ALIGNMENT TRANS-CATHETER AORTIC VALVE IMPLANTATION

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