Mountain air or heart risk? trial asks if high altitude is safe for aortic stenosis patients.
NCT ID NCT06894550
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial investigates whether a short stay at high altitude (up to 3,545 meters) is safe for people with asymptomatic moderate or severe aortic stenosis. Participants will undergo heart tests—including ECG, echocardiography, and exercise stress tests—both at low altitude and after ascending. The goal is to measure changes in exercise capacity, heart function, and rhythm to see if altitude poses a risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- short-term high-altitude exposure (ascending to 3545 m above sea level)
- What this could lead to
- If safe, it could provide evidence to update guidelines, allowing people with aortic stenosis to enjoy high-altitude travel without unnecessary restrictions.
- What could go wrong
- This is a small, early-stage observational study with only 41 participants. It measures surrogate markers, not hard outcomes like heart attacks or death, so results may not be definitive.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Hospital Inselspital, Bern
Bern, Canton of Bern, CH-3010, Switzerland
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