Altitude sickness

This study tests whether the asthma inhaler Advair HFA can prevent high altitude pulmonary edema (HAPE), a dangerous buildup of fluid in the lungs at high altitudes. Researchers will give the drug or a placebo to 60 healthy volunteers and people prone to HAPE, then measure their …

This study tests if a special high-flow oxygen mask works better than standard oxygen for people with high-altitude pulmonary edema (fluid in the lungs from climbing too high too fast). About 200 adults who develop symptoms within 7 days of reaching high altitude will be randomly…

This study tests whether a procedure called erythrocytapheresis—which removes extra red blood cells from the blood using a machine—can safely reduce symptoms of chronic mountain sickness. The trial will enroll 112 long-term high-altitude residents with very high hemoglobin levels…

This study looks at whether low oxygen levels (like at high altitudes) increase the risk of heat stress during moderate work in hot environments. Twenty healthy young and older men will walk on a treadmill in a hot room, once with normal oxygen and once with low oxygen. Researche…

This study looks at whether being treated at a high-altitude hospital affects survival for children with acute respiratory distress syndrome (severe lung failure). Researchers will collect data from 1,600 children in intensive care units around the world. The goal is to understan…

This study looks at how simulated high altitude (2,500 m and 4,000 m) affects the right side of the heart in people with well-controlled asthma. Eighteen participants will breathe special gas mixtures to mimic altitude while resting and doing light exercise. The goal is to learn …

This study tests whether soaking in hot spring water helps teenage rowers recover from central fatigue and maintain mental sharpness during high-altitude training. Twenty-seven athletes aged 12-16 will either rest normally, bathe in plain warm water, or bathe in sodium bicarbonat…

This study looks at whether taking hot spring baths can help young athletes recover their thinking skills and physical performance while training at simulated high altitudes. Twenty-seven healthy teens who already train regularly will be randomly assigned to hot spring baths, pla…

This study aims to see if analyzing the chemicals in a child's breath can help diagnose and monitor diseases like asthma, neurological disorders, and type 1 diabetes. Researchers will collect breath samples from up to 3,600 children and teens to find patterns linked to these cond…

This study looks at how the right side of the heart works when there is less oxygen, like at high altitudes. It involves 18 adults who have had HAPE (high-altitude pulmonary edema) in the past. Participants breathe special gas mixtures to mimic altitudes of 2,500 and 4,000 meters…

This study looks at how sleeping at high altitude (2,877 meters) affects the sleep quality of 32 employees at Pic du Midi. Researchers will compare nights spent at home versus nights spent at the summit using sleep recordings. The goal is to understand sleep changes in people who…

This study looks at how the right side of the heart works when oxygen levels drop, like at high altitudes. Healthy volunteers will breathe special gas mixtures that mimic altitudes of 2,500 and 4,000 meters, both at rest and during light cycling. The goal is to create a baseline …

This study looks at why pregnant women living at high altitudes have higher rates of preeclampsia and poor fetal growth. Researchers will collect tissue samples from women having scheduled C-sections in Denver (low altitude) and Summit County (high altitude) to compare how their …

This study looks at how living at high altitudes affects the body's iron levels. Iron is important for carrying oxygen in the blood, and high altitudes may change how much iron you absorb and lose. Researchers will give 120 healthy adults a special iron tracer and track it over a…

This study looks at how low oxygen levels (like at high altitudes) affect mood and anxiety in people with depression or anxiety disorders compared to healthy individuals. 68 participants will spend six hours in a special chamber that simulates 3,800 meters altitude, and their fee…