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Altitude sickness
MONDO:0006625Multiple symptoms associated with reduced oxygen at high altitude.
44 clinical trials for this condition and its sub-types.
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Altitude drug may protect Women's lungs better than Men's
Disease control CompletedThis study tested whether the drug acetazolamide (commonly used for altitude sickness) reduces pressure in the lung arteries differently in women compared to men when traveling to 3,600 meters. Over 300 healthy, non-smoking adults took either the drug or a placebo starting 24 hou…
Phase: PHASE4 • Sponsor: University of Zurich • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Altitude sickness drug put to the test: do women need a different dose?
Disease control CompletedThis study looked at whether the drug acetazolamide (Diamox) prevents acute mountain sickness (AMS) equally well in women and men. Over 300 healthy adults traveled to high altitude and took either the drug or a placebo. The goal was to see if women, who may have higher drug level…
Phase: PHASE4 • Sponsor: University of Zurich • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Race Walkers' breathing under the microscope: altitude study reveals hidden lung strain
Diagnosis CompletedThis study looked at whether training at high altitudes causes or worsens exercise-induced bronchoconstriction (EIB) in 64 elite race walkers. Participants completed lung function tests, treadmill challenges, and blood draws at both low and high altitudes over 2-4 months. The goa…
Sponsor: Shanghai University of Sport • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Oxygen boost helps highlanders breathe easier at altitude
Symptom relief CompletedThis study looked at whether giving extra oxygen to people who live high in the mountains and have high altitude pulmonary hypertension (a type of high blood pressure in the lungs) helps them walk farther. Twenty-four participants completed the trial. Researchers measured how far…
Phase: NA • Sponsor: University of Zurich • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Hot springs boost altitude training for young athletes?
Knowledge-focused CompletedThis study tested whether taking hot spring baths (38°C for 20 minutes, three times a week) helps healthy teen athletes adapt to training at 1600 meters altitude. 27 participants were split into three groups: hot spring baths, hot water baths, or standard recovery. Researchers me…
Phase: NA • Sponsor: Macao Polytechnic University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Women's cycle phase linked to mountain sickness risk
Knowledge-focused CompletedThis study looked at whether the phase of a woman's menstrual cycle affects her chances of getting acute mountain sickness (AMS) when traveling to high altitude. Researchers followed 91 healthy women as they spent two days at 3600 meters (about 11,800 feet). The goal was to see i…
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Pilot body under pressure: new study tests oxygen effects on flight skills
Knowledge-focused CompletedThis study looked at how low oxygen (like at high altitudes) affects pilots' bodies and their ability to fly. 17 healthy volunteers did flight simulator tasks while breathing air that mimicked 8,000 or 12,000 feet. Researchers measured heart rate, blood pressure, oxygen levels, a…
Phase: NA • Sponsor: University of Texas, El Paso • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Mountain rescue under the microscope: does thin air hurt patient care?
Knowledge-focused CompletedThis study looked at how being at high altitude (over 3,400 meters) affects the performance of highly trained medical rescuers. Twenty doctors performed simulated patient care scenarios at altitude, with and without extra oxygen, and after spending a night there. The goal was to …
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could a diabetes pill boost high-altitude exercise performance?
Knowledge-focused CompletedThis study looked at whether pioglitazone, a drug used for diabetes, can help the body use sugar from food during exercise at high altitude. Nine healthy men took either the drug or a placebo for five days, then exercised on a treadmill in a chamber simulating high altitude. Rese…
Phase: PHASE4 • Sponsor: United States Army Research Institute of Environmental Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Mountain air vs. machine: which altitude experience is more intense?
Knowledge-focused CompletedThis study looked at how being at a real high altitude (3,000 meters in a mountain hut) compares to a machine that mimics low-oxygen conditions. Twenty healthy adults took part, and researchers measured things like brain oxygen, blood oxygen, heart rate, sleep quality, and altitu…
Phase: NA • Sponsor: University of Applied Sciences and Arts of Southern Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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High-Altitude lung patients breathe better at lower elevations, study finds
Knowledge-focused CompletedThis study looked at 24 people with high-altitude pulmonary hypertension who live above 2500 meters. Researchers measured their sleep breathing at 3200 meters and again after moving to 760 meters. The goal was to see if lower altitude improves oxygen levels and reduces breathing …
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Mountain dwellers' lung condition improves at lower altitude, study finds
Knowledge-focused CompletedThis study looked at 24 people with high altitude pulmonary hypertension who live above 8,200 feet. Researchers measured how far they could walk in 6 minutes at their home altitude (10,500 feet) and after moving to a lower altitude (2,500 feet). The goal was to see if relocating …
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Descending from the peaks: lower altitude eases lung pressure in high-altitude patients
Knowledge-focused CompletedThis study looked at 24 people with high altitude pulmonary hypertension (HAPH) who live above 2,500 meters. Researchers measured their lung blood pressure at 3,200 meters and then after moving to 760 meters for one night and seven nights. The goal was to see if simply being at a…
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can extra oxygen ease High-Altitude heart strain?
Knowledge-focused CompletedThis study looked at whether giving extra oxygen can lower blood pressure in the lungs of people who live above 2500 meters and have high altitude pulmonary hypertension. Researchers measured heart changes with ultrasound in 48 highlanders while they breathed either oxygen or reg…
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC