Altitude drug may protect Women's lungs better than Men's
NCT ID NCT06498505
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether the drug acetazolamide (commonly used for altitude sickness) reduces pressure in the lung arteries differently in women compared to men when traveling to 3,600 meters. Over 300 healthy, non-smoking adults took either the drug or a placebo starting 24 hours before ascent. Researchers measured changes in heart and lung function using ultrasound to see if sex influences the drug's effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- acetazolamide
- What this could lead to
- If successful, this could show that acetazolamide helps prevent high-altitude pulmonary hypertension, especially in women.
- What could go wrong
- This is a completed Phase 4 trial in healthy volunteers, not patients. The effect may be small or not apply to people with existing health conditions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Center for Cardiology and Internal Medicine
Bishkek, Bishkek, 720040, Kyrgyzstan
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