Altitude drug may protect Women's lungs better than Men's
NCT ID NCT06498505
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether the drug acetazolamide (commonly used for altitude sickness) reduces pressure in the lung arteries differently in women compared to men when traveling to 3,600 meters. Over 300 healthy, non-smoking adults took either the drug or a placebo starting 24 hours before ascent. Researchers measured changes in heart and lung function using ultrasound to see if sex influences the drug's effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
acetazolamide
What this could lead to
If successful, this could show that acetazolamide helps prevent high-altitude pulmonary hypertension, especially in women.
What could go wrong
This is a completed Phase 4 trial in healthy volunteers, not patients. The effect may be small or not apply to people with existing health conditions.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HIGH ALTITUDE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
National Center for Cardiology and Internal Medicine
Bishkek, Bishkek, 720040, Kyrgyzstan