Altitude sickness

This study aims to improve treatment for severe high altitude pulmonary edema (fluid in the lungs) and cerebral edema (brain swelling). Researchers will test breathing support devices and inhaled nitric oxide gas in over 3,000 patients in Tibet. The goal is to speed up recovery, …

This study tests whether a non-invasive ventilator (a mask that helps you breathe at night) can lower hemoglobin levels in people with high-altitude polycythemia, a condition where the blood becomes too thick due to low oxygen. About 70 adults living at high altitudes will either…

This study tests a device that temporarily stops blood flow to the arms in short cycles, aiming to help people with high altitude polycythemia — a condition where the body makes too many red blood cells at high altitudes. The trial will involve 222 adults living above 2,500 meter…

This study tests whether a single injection of fremanezumab, a drug used to prevent migraines, can stop acute mountain sickness (AMS) in healthy adults. Thirty volunteers will receive either the drug or a placebo one week before climbing to a high-altitude hut. Researchers will t…

This study looks at whether watching cartoons or listening to breath-synchronized interactive stories can help children aged 6-9 feel less afraid and more comfortable while using a nebulizer for breathing medication. About 96 children with respiratory conditions will be randomly …

This study tests if applying cold (cryotherapy) to the wrist before a blood draw from the artery can reduce pain. It involves 258 adults with chronic respiratory diseases who need this test. The goal is to find a simple, drug-free way to make the procedure less painful.

This study looks at whether being at a moderate altitude (like 4,000 meters) can hurt your ability to remember to do things later, called prospective memory. Fifty healthy adults will take memory tests while breathing low-oxygen air or normal air in a chamber. Researchers also wa…

This study looks at whether a medicine called iloprost can be given to people with severe frostbite (grades 3-4) in remote, high-altitude places like Mount Everest. The goal is to see if it's safe and practical to start treatment before reaching a hospital. Ten adults with severe…