Altitude sickness

This study follows 20,000 healthy Chinese adults aged 40-75 living at various altitudes to see if chronic low oxygen levels increase the risk of multiple system atrophy (MSA), a rare and fatal brain disease. Participants undergo checkups and overnight oxygen monitoring, then are …

This study tests whether acetazolamide, a drug already used for altitude sickness, can reduce inflammation and immune system activation caused by high altitude. Nineteen healthy adults will take either the drug or a placebo before and during a stay at 3800 meters. Researchers wil…

This study looks at whether human milk oligosaccharides (HMOs), a key ingredient in breast milk, can help adults living in Antarctica for a year maintain a healthy gut, immune system, and metabolism. Twenty-six healthy adults will take either an HMO supplement or a placebo. Resea…

This study follows 30 lung transplant recipients and healthy volunteers as they prepare for and climb Mount Aconcagua (6,971 meters). Participants first use a special tent at home for eight weeks to get used to lower oxygen levels. Then, a team monitors their lung function, oxyge…

This study tests whether a drug can help red blood cells work better in low-oxygen (hypoxia) and cold (hypothermia) conditions, which are common in high-altitude or military environments. Researchers will measure how the drug affects red blood cell energy and antioxidant defenses…

This study aims to see if a simple, non-invasive breathing test can accurately measure the acidity (pH) in the airways, which is often abnormal in lung diseases. Researchers will compare results from this breath test with standard methods in 150 healthy volunteers and people with…