Mountain air on tap: scientists test heart under low oxygen

NCT ID NCT07431567

Recruiting now Knowledge-focused Sponsor: Mona Lichtblau Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the right side of the heart works when oxygen levels drop, like at high altitudes. Healthy volunteers will breathe special gas mixtures that mimic altitudes of 2,500 and 4,000 meters, both at rest and during light cycling. The goal is to create a baseline for healthy hearts, so doctors can later better support patients with heart or lung conditions who want to exercise in the mountains.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: normobaric hypoxia (simulated altitude via special gas mixture)
What this could lead to: If successful, this study could help doctors better understand how the heart handles low oxygen, potentially improving care for people with heart or lung conditions who travel to high altitudes.
What could go wrong: This is a small, early-stage study in healthy volunteers, not patients. The results may not directly apply to people with heart or lung disease, and the simulated altitude may not fully reflect real mountain conditions.

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Conditions

The condition(s) this trial relates to.

altitude sickness Dyspnea Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALTITUDE HYPOXIA HYPOXIA NORMOBARIC HYPOXIA RIGHT HEART FUNCTION

Contacts and locations

Locations

Consultant Clinic of Pulmonology, University Hospital of Zurich
RECRUITING

Zurich, Canton of Zurich, 8091, Switzerland
Consultant Clinic of Pulmonology, University Hospital of Zurich
NOT_YET_RECRUITING

Zurich, 8091, Switzerland

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