Hidden toll of routine ICU procedure revealed: suctioning may spike pain and stress

NCT ID NCT06692400

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study investigates whether endotracheal tube suctioning—a routine procedure to clear airways in intubated ICU patients—causes pain and biological stress. Researchers will measure pain using a behavioral observation tool and check blood for markers of oxygen shortage and oxidative stress before and after suctioning. The study includes adults with flu, pneumonia, COVID, or sepsis who are on ventilators. Findings could help tailor pain relief for patients who cannot speak.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better pain management protocols for ICU patients who cannot speak, improving their comfort and care.
What could go wrong
This is a small, early-stage observational study. Results may not apply to all ICU patients, and the blood markers measured may not fully capture stress or pain.

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Conditions

The condition(s) this trial relates to.

COVID-19 Critical Illness Hypoxia infectious disease with sepsis influenza Pain, Procedural pneumonia Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Loma Linda University Medical Center Troesh Medical Campus

    RECRUITING

    Loma Linda, California, 92354, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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