Loma Linda University

This study aims to find out if a low-dose aspirin pill (81 mg) works as well as a higher-dose pill (325 mg) at preventing strokes in people who have injured the blood vessels in their neck from blunt force, like in a car crash. Researchers will enroll about 98 adults with this sp…

This study aims to find out which of two common blood pressure medications works better for women who develop high blood pressure after giving birth. Researchers will compare oral nifedipine versus oral labetalol in 500 postpartum women. The goal is to determine which medication …

This study is testing a new treatment plan for people with pancreatic cancer that can be removed by surgery. The goal is to see if giving strong chemotherapy and targeted radiation *before* the operation helps surgeons remove all the cancer cells more effectively. Researchers wil…

This study is testing whether using special low-radiation X-ray settings during a bladder treatment procedure is as safe and effective as the standard high-radiation settings. The procedure, called sacral neuromodulation, treats overactive bladder and incontinence. Researchers wi…

This study is testing a new support program for families where children have experienced stressful or traumatic events in childhood. It connects families with a pediatrician, a community health worker, and a parenting coach who work together to provide resources and build resilie…

This study is testing whether a team-based support program in the hospital helps people with HIV get connected to ongoing specialist care after they go home. It will enroll 250 adults who are hospitalized and not currently receiving proper HIV treatment. The main goal is to see i…

This large study is testing if washing the surgical area with a diluted antiseptic solution (povidone-iodine) during emergency abdominal surgery is better at preventing wound infections than using standard saltwater (saline). It will involve 1,100 adult patients and compare infec…

This study is testing two different exercise approaches to help young rowers manage low back pain. Researchers want to see if lighter training with restricted blood flow works as well as traditional heavy lifting for improving performance while being safer. The study involves 120…

This study is comparing two standard surgical techniques for removing a testicle when cancer is suspected. Researchers want to see if a modified technique that spares a specific muscle layer causes less pain after surgery, reduces the need for opioid painkillers, and leads to few…

This study is testing a gentle, hands-on therapy called strain-counterstrain to see if it can reduce pain from a tight piriformis muscle in the buttock. Researchers will compare the real treatment to a sham treatment in 30 adults. They will measure changes in pain levels and how …

This study aims to see if a new powered prosthetic knee helps people with above-knee limb loss walk using less energy, especially on slopes, compared to their usual knee. Researchers will measure oxygen use and exertion while participants walk on a treadmill. The goal is to under…

This small pilot study is checking if it's practical to research whether melatonin supplements help teenagers who have trouble sleeping. It will enroll about 80 teens with sleep issues to see if taking melatonin for two weeks improves their sleep length and helps them manage thei…

This study is testing whether a short-term strength training program can improve health for women after menopause. Researchers will compare 46 sedentary women, with half doing 8 weeks of circuit training and half maintaining their usual routine. They will measure changes in muscl…

This study is testing whether adding a special stitching technique (lateral pharyngoplasty) to a standard tonsil removal helps children recover better. Researchers want to see if kids have less pain, start eating normally faster, and have fewer bleeding problems after surgery. Th…

This study is testing if giving a single dose of gabapentin two hours before wisdom teeth removal can help control pain while reducing the need for opioid painkillers during and after the procedure. About 98 adults having their wisdom teeth pulled will receive either gabapentin o…

This study is testing if limited ankle flexibility contributes to knee pain during movements like squatting. Researchers will compare two groups of women with chronic knee pain: one doing specific exercises to improve ankle motion, and a minimal intervention group. The goal is to…

This study is testing whether adding a health and resilience program to the regular coursework for occupational therapy students helps them feel better. Researchers want to see if the program reduces students' symptoms of anxiety and depression and improves their lifestyle habits…

This study aims to understand how a 16-week social skills training program affects the brain in teenagers with autism or schizophrenia. Researchers will use MRI brain scans before and after the training to see if brain connections and chemistry change. They will compare these tee…

This study aims to compare two different nerve locations in the arm for monitoring muscle relaxation during surgery. Researchers want to see if the median nerve works as well as the standard ulnar nerve for tracking how well muscle-relaxing medications are working. The study invo…

This study aims to understand how two different non-invasive treatments work for diabetic nerve pain. Researchers will compare a specialized therapy called INF® Therapy with standard physical therapy in 40 adults with type 2 diabetes and nerve damage. They'll measure blood flow, …

This study aims to understand the relationship between hearing processing difficulties, sleep problems, and other traits in children and teens with autism. Researchers will compare two groups: those with and without a specific hearing processing disorder. Participants will comple…

This study aims to understand if what a doctor wears influences how much patients trust them. Researchers will ask 200 hospitalized patients to complete surveys about their doctors, who will alternate between wearing surgical scrubs and professional attire with a white coat. The …

This study aims to understand how quickly the gums change shape after a temporary dental implant crown is removed. Researchers will scan the gum area around the implant immediately after crown removal and several times over 15 minutes to measure any shifts. The goal is to help de…