Proton beam zaps liver tumors without surgery in new trial

NCT ID NCT01697371

Recruiting now Disease control Sponsor: Loma Linda University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a precise type of radiation called proton beam therapy for people with liver tumors that have spread from other cancers and cannot be removed by surgery. The treatment delivers high-dose radiation in three sessions over two weeks. The goal is to see if it is safe and can control the tumors for at least two years. The trial enrolls 35 adults with up to three small liver tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Proton beam radiation
What this could lead to: If successful, this could offer a non-surgical option to control liver metastases, potentially improving survival and quality of life for patients who cannot have surgery.
What could go wrong: This is an early-phase trial with only 35 participants, so results may not apply broadly. The treatment may cause side effects like fatigue or liver damage, and it is not a cure.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER METASTASES

Contacts and locations

Locations

Loma Linda University Medical Center
RECRUITING

Loma Linda, California, 92354, United States

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