A new clue in the fight against colorectal cancer recurrence?

NCT ID NCT07744139

Not yet recruiting Knowledge-focused Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Source: ClinicalTrials.gov ↗

First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study looks at whether a combination of immune cell activity, genetic changes, and imaging features can help predict if colorectal cancer that has spread to the liver will come back after surgery. Researchers will analyze tumor tissue, blood samples, and scans from about 210 patients who had liver surgery for colorectal cancer metastases. The goal is to build a model that could one day help doctors personalize follow-up care and catch recurrence earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a predictive tool that helps doctors identify patients at higher risk of cancer recurrence after liver surgery, enabling more personalized follow-up and treatment decisions.
What could go wrong: This is an observational study, so it won't test a new treatment. The predictive model may not prove accurate enough for routine use, and findings from this single-center study may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colon carcinoma colonic neoplasm colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLO-RECTAL CANCER COLON CANCER LIVER METASTASES

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Other studies related to the condition(s) this trial covers.