A new way to read CT scans may predict which liver surgery patients will develop Life-Threatening failure

NCT ID NCT07727759

Not yet recruiting Knowledge-focused Sponsor: Minia University Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Aug 12, 2026 · Updated 4 times

Summary

This study tests whether adding a technique called vascular deformation mapping (VDM) to standard CT scans can better predict liver failure after major liver surgery. Researchers will analyze routine preoperative CT images from over 1,000 adults undergoing removal of at least three liver segments. The goal is to develop a risk score that helps surgeons identify high-risk patients before the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Preoperative CT volumetry with hepatic vascular deformation mapping (VDM)
What this could lead to: If successful, this could give surgeons a practical tool to identify high-risk patients before liver surgery, potentially reducing life-threatening liver failure.
What could go wrong: This is an observational study, not a treatment trial. The prediction model may not perform as well in real-world settings or may not improve outcomes.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver and intrahepatic bile duct neoplasm liver failure Liver Neoplasms nutmeg liver Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA, HEPATOCELLULAR HEPATIC CONGESTION LIVER FAILURE LIVER METASTASES LIVER NEOPLASMS POST-HEPATECTOMY LIVER FAILURE POSTOPERATIVE COMPLICATIONS

Contacts and locations

Locations

Liver and GIT Hospital, Faculty of Medicine, Minia University

Minya, Minya Governorate, 61519, Egypt
Maadi Armed Forces Medical Compound - Department of Liver and Pancreas Surgery and Liver Transplantation

Maadi, Egypt
National Liver Institute, Menoufia University

Shibīn al Kawm, Egypt

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