CARCINOMA, HEPATOCELLULAR
Clinical trials for CARCINOMA, HEPATOCELLULAR explained in plain language.
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New hope for liver cancer: pfizer tests experimental drug
Disease control Recruiting nowThis study tests a new drug called PF-08634404, given alone or with another drug (ipilimumab), in adults with advanced liver cancer that cannot be surgically removed. The goal is to check safety, side effects, and whether the drug shrinks tumors. About 138 participants will recei…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: PHASE1, PHASE2 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New combo therapy aims to shrink untreatable liver tumors
Disease control Recruiting nowThis study tests a powerful combination of treatments for people with advanced liver cancer that cannot be surgically removed. The approach uses heat-based ablation to destroy the main tumor, followed by targeted therapy (lenvatinib), immunotherapy (tislelizumab), and a procedure…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: NA • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New drug AST-201 targets Hard-to-Treat cancers in first human trial
Disease control Recruiting nowThis early-stage study tests a new drug called AST-201 in about 70 adults with advanced solid tumors that have a protein called GPC3. The main goal is to check the drug's safety and find the right dose. Researchers will also measure how the drug moves through the body and look fo…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: PHASE1 • Sponsor: Aptamer Sciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New triple-drug attack targets hard-to-treat liver cancer
Disease control Recruiting nowThis study tests a new drug, Irpagratinib, added to two standard drugs (Atezolizumab and Bevacizumab) for people with advanced liver cancer that cannot be removed by surgery. The goal is to see if the combination is safe and shrinks tumors. About 33 adults with a specific genetic…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New drug combo aims to stop liver cancer in its tracks
Disease control Recruiting nowThis phase 2 trial is testing whether adding the immunotherapy drug tislelizumab after standard liver-directed treatments (like radiation) can help control inoperable liver cancer. About 35 adults with hepatocellular carcinoma who have not had systemic therapy will receive tislel…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Blood test could outshine ultrasound in liver cancer screening
Diagnosis Recruiting nowThis phase IV trial will enroll 5,500 people with liver cirrhosis or chronic hepatitis B—conditions that raise liver cancer risk. Participants are randomly assigned to either standard ultrasound screening or a new blood test called GALAD, which measures three proteins. The goal i…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: PHASE4 • Sponsor: University of Texas Southwestern Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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MRI vs ultrasound: which scan saves more lives from liver cancer?
Prevention Recruiting nowThis study tests if a faster MRI scan, combined with a blood test, can find liver cancer earlier than the standard ultrasound in people with cirrhosis. The goal is to catch cancer at an early, more treatable stage and reduce deaths from liver cancer. About 4,700 veterans with cir…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Prevention
Last updated Jun 27, 2026 14:00 UTC
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New study aims to uncover how liver cancer affects older patients
Knowledge-focused Recruiting nowThis study is observing 84 adults with advanced liver cancer that cannot be removed by surgery. Researchers want to learn how the disease progresses, what treatments are used, and what side effects occur, especially in patients 65 and older. Participants will complete geriatric a…
Matched conditions: CARCINOMA, HEPATOCELLULAR
Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC