Radiation and immunotherapy join forces against Hard-to-Treat liver metastases
NCT ID NCT06794086
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests whether combining a precise form of radiation (SBRT) with an immunotherapy drug (PD-1 monoclonal antibody) can help people whose colorectal cancer has spread to the liver and cannot be removed surgically. The trial enrolls adults aged 18 to 75 with a specific type of colorectal cancer (pMMR/MSS). The goal is to see if this combination shrinks tumors and improves outcomes, while monitoring for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PD-1 monoclonal antibody (a type of immunotherapy) plus stereotactic body radiation therapy (SBRT, a precise form of radiation)
What this could lead to
If successful, this combination could offer a new treatment option for people with colorectal cancer that has spread to the liver and cannot be removed by surgery, potentially shrinking tumors and improving survival.
What could go wrong
This is a small, early-phase study with only 24 participants, so results may not apply to everyone. The combination of radiation and immunotherapy can cause side effects such as fatigue, liver inflammation, or immune-related reactions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sixth Affiliated Hospital, Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510065, China
Contact Phone: •••-•••-•••• Email: •••••@•••••