New proton combo aims to improve esophageal cancer treatment
NCT ID NCT01684904
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial is testing a combination of proton radiation and chemotherapy (carboplatin and paclitaxel) before surgery for patients with resectable esophageal or esophagogastric junction cancer. The goal is to see if this approach is safe, tolerable, and effective at improving overall survival. The study enrolls 38 participants with specific stages of the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
proton radiation combined with carboplatin and paclitaxel chemotherapy
What this could lead to
If successful, this could offer a more effective and less toxic treatment option for esophageal cancer patients, potentially improving survival rates.
What could go wrong
This is a small, early-phase trial with only 38 participants, so results may not apply to everyone. The treatment still carries risks of side effects from both chemotherapy and radiation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Loma Linda University Medical Center
RECRUITINGLoma Linda, California, 92354, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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