New drug combo aims to stop Chemo-Induced nausea in cancer patients

NCT ID NCT07617246

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a combination of two drugs, fosrolapitant and palonosetron, plus a steroid, can prevent nausea and vomiting caused by chemotherapy and immunotherapy in people with esophageal or lung cancer. About 120 participants will receive the drug before each chemo cycle. Researchers will track how many patients have no vomiting or need for rescue medication during the first week after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fosrolapitant and Palonosetron Hydrochloride for Injection combined with dexamethasone acetate

What this could lead to

If it works, this could provide a more effective way to prevent nausea and vomiting during cancer treatment, improving patients' quality of life.

What could go wrong

This is an early phase 2 trial with only 120 participants, so results may not apply to everyone. The drug may not work better than existing options, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • SAHZhejiangU

    RECRUITING

    Hangzhou, Zhejiang, 313000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••