Blood test could predict esophageal cancer return

NCT ID NCT05704530

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study is looking at whether a blood test (liquid biopsy) can find tiny bits of cancer DNA left behind after treatment for esophageal cancer. Researchers will collect blood samples from 248 patients before, during, and after standard treatment. The goal is to see if this test can improve cancer staging and predict if the cancer will come back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AZ Delta

    RECRUITING

    Roeselare, Belgium

    Contact

    Contact

  • UZ Gent

    RECRUITING

    Ghent, Belgium

    Contact

  • UZA

    RECRUITING

    Antwerp, Belgium

    Contact

  • UZLeuven

    RECRUITING

    Leuven, Belgium

    Contact

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

blood sample (liquid biopsy for ctDNA)

What this could lead to

If successful, this could lead to a more accurate way to stage esophageal cancer and predict if the cancer will come back after treatment.

What could go wrong

This is an early-stage observational study, so it may not prove that liquid biopsies improve outcomes. The test might not be sensitive enough to detect all cases of residual cancer.

Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.