Loma Linda University

This study is for people with pancreatic cancer that can be removed by surgery. It tests whether giving chemotherapy and radiation before surgery can help surgeons remove all the cancer. About 30 adults will take part. The goal is to see if this approach leads to better outcomes.

This study tests whether washing the wound and abdominal cavity with a diluted iodine solution during emergency abdominal surgery reduces the risk of surgical site infections compared to using saline. About 1,100 adults aged 18 to 80 with certain types of wounds will take part. T…

This study tests whether a team-based program (ARTAS) can help people with HIV get linked to care after leaving the hospital and reduce the chance of being readmitted. About 250 adults with HIV who are not currently on treatment or seeing a specialist will take part. Researchers …

This study looks at whether a low dose (81 mg) of aspirin works as well as a higher dose (325 mg) to prevent strokes in people who have injured the blood vessels in their head or neck from a blunt force, like a car accident. About 98 adults will be randomly assigned to one of the…

This study tests whether a powered, computer-controlled prosthetic knee helps people with above-knee amputations use less energy while walking on flat and sloped surfaces compared to their usual prosthesis. Researchers will measure oxygen use, balance confidence, and perceived ef…

This study tests whether taking 600 mg of gabapentin two hours before wisdom tooth extraction can lower pain and reduce the need for opioid painkillers afterward. About 98 adults will be randomly assigned to receive either gabapentin or a placebo. Researchers will track opioid us…

This study looks at two non-invasive treatments for nerve pain caused by type 2 diabetes: Intraneural Facilitation Therapy (INF) and standard physical therapy. Researchers want to understand how these treatments work by measuring things like heart rate, blood flow, and inflammati…

This study tests a non-invasive technique called Strain-Counterstrain to relieve pain caused by the piriformis muscle, a common source of low back and leg discomfort. Researchers will enroll 30 adults aged 18 to 65 who have a tender spot in that muscle. The treatment involves gen…

This study looks at whether a special low-weight workout using blood flow restriction cuffs can help teenage rowers with mild or recurring low back pain. Researchers want to see if this method is as effective as heavy lifting for improving performance and preventing re-injury, bu…

This study compares two common blood pressure medicines, Nifedipine and Labetalol, to see which one works better and is safer for women who develop high blood pressure after giving birth. About 500 new mothers will take one of the two drugs, and researchers will track how well th…

This study looks at two common ways to remove a testicle affected by cancer. The goal is to find out if one method causes less pain and requires fewer painkillers after surgery. About 80 adults with testicular cancer will take part, and they will report their pain levels and reco…

This study looks at whether short-term circuit strength training can help sedentary postmenopausal women improve muscle mass, sleep, balance, and quality of life. Researchers will also measure inflammation levels. The goal is to provide evidence that this type of exercise can sup…

This study looks at whether using lower radiation settings during a procedure to implant a nerve stimulator for overactive bladder is safe and effective. About 44 adults with overactive bladder will be randomly assigned to receive either standard or reduced radiation during the l…

This study looks at whether taking melatonin helps teenagers (ages 13-17) who have trouble sleeping fall asleep faster and sleep longer. Participants will take melatonin for two weeks and a placebo for two weeks, and their sleep will be tracked with a wrist monitor. The goal is t…

This study tests whether adding a small extra step (lateral pharyngoplasty) to standard tonsil removal helps children ages 3-17 recover better. Researchers will compare pain levels, how soon kids can eat and drink normally, and the risk of bleeding after surgery. The goal is to f…

This study looks at two different nerves in the arm—the ulnar and median nerves—to see if both can reliably measure muscle relaxation during surgery. About 32 adults having elective surgery will be monitored at both nerve sites. The goal is to find out if the median nerve works j…

This study looks at whether poor sleep contributes to central auditory processing disorder (CAPD) in children and teens with autism. Researchers will compare those with and without CAPD using parent reports and clinical tests. The goal is to better understand how hearing, sleep, …

This study looks at why teens with autism or schizophrenia struggle with social interactions. Researchers will use brain scans to compare brain activity and chemistry in 90 teens before and after a 16-week social skills program. The goal is to find out how the training changes th…

This study looks at whether adding health and resilience programs to the occupational therapy curriculum helps students feel better and live healthier. About 130 students will take part in the programs as part of their regular coursework and complete surveys before and after. The…

This study looks at how the gums around a dental implant change shape when the temporary crown is taken off. Researchers want to know how much time is needed before the gums settle enough to make an accurate mold for a new crown. About 34 adults with a front tooth implant will ha…

This study looks at how limited ankle movement affects knee pain in women with patellofemoral pain (pain around the kneecap). Researchers will measure ankle flexibility and how it changes the way participants do a single-leg squat. The goal is to better understand the connection …

This study looks at whether what a doctor wears affects how much patients trust them. About 200 adults staying in a hospital medical-surgical unit will fill out a one-time survey about their preferences for doctor attire, like a white coat versus surgical scrubs. The goal is to u…

This study looks at whether magnesium sulfate, a common pain treatment given during surgery, changes the signals used to monitor nerves during spine or brain operations. Researchers will give 50 adults either magnesium or a placebo and compare nerve signal readings. The goal is t…

This study tests a program that brings together pediatricians, community health workers, and parenting educators to support families with adverse childhood experiences (ACEs). The goal is to lower stress and improve health in children ages 3 to 11. Researchers will compare famili…