HYPOXIA

This study is testing if teaching hospital staff to aim for a specific, slightly lower oxygen level (90-96%) in adult ICU patients on breathing machines helps them recover faster. The main goal is to see if this approach reduces the number of days patients need the ventilator. It…

This study aims to find out if a high-flow nasal cannula is better than a standard face mask at helping chest trauma patients breathe without needing a tube placed down their throat. It will involve 100 adults who have suffered chest injuries and are struggling with low oxygen le…

This study is testing a new medical device designed to help obese patients breathe better and maintain safe oxygen levels while they are sedated for stomach and colon exams. The device combines several functions like oxygen support and airway management into one tool. Researchers…

This study is testing a modified breathing tube designed to make anesthesia safer during surgery. It allows doctors to easily switch between two different ventilation methods without needing extra equipment. The goal is to reduce risks like low oxygen levels during procedures req…

This study is testing two new, low-cost pulse oximeter devices designed for children in low-resource clinics in Cape Town, South Africa. It aims to see if these devices help healthcare workers better identify babies and toddlers with dangerously low oxygen levels from pneumonia, …

This study is testing whether a special high-flow nasal oxygen device can prevent dangerous drops in oxygen levels during sedated endoscopy procedures. The research focuses on 600 patients who are at high risk for obstructive sleep apnea and are scheduled for gastrointestinal exa…

This study is testing whether two simple, non-drug approaches can help people exercise more easily in low-oxygen conditions, like at high altitude. Healthy, active adults will try either breathing muscle training, drinking beetroot juice (a natural nitrate source), both, or neith…

This study is testing whether a sedative called remimazolam, when used with a painkiller, is safer than the current standard sedative during IVF egg retrieval. It aims to reduce episodes of low oxygen levels (hypoxia), which is a common risk during this procedure. Researchers wil…

This study is testing if doctors can skip a standard suctioning step when removing a patient's breathing tube after surgery. Researchers want to see if skipping this step reduces coughing and sore throat after waking up, without causing problems with low oxygen levels. About 400 …

This study is testing a modified oxygen delivery method for patients undergoing sedated lung exams (bronchoscopy). Researchers are using a thinner breathing tube inserted through the nose to see if it provides better oxygen flow and reduces the risk of low oxygen levels during th…

This study aims to understand how the healthy heart, especially its right side, responds to low-oxygen conditions like those at high altitudes. Researchers will simulate different altitudes (sea level, 2,500m, and 4,000m) for 18 healthy participants while they rest and do light e…

This study aims to check how accurate common finger-clip oxygen monitors (pulse oximeters) are, especially for people with different skin colors. Researchers will temporarily lower oxygen levels in 10,000 healthy volunteers and compare the device readings to gold-standard blood t…

This study aims to understand how blood vessels in the arm respond to low oxygen levels in healthy women at different stages of menopause. Researchers will compare younger premenopausal women, perimenopausal women, and older postmenopausal women to see how aging and menopause aff…

This study aims to understand how low oxygen levels at high altitudes affect mood and stress in people with anxiety and depression. Researchers will compare 68 participants—some with these mental health conditions and some without—by having them spend time in a special chamber th…