HYPOXIA

This study tested whether breathing air with low and then high oxygen before heart bypass surgery could help protect the heart from damage. 120 adults scheduled for bypass surgery took part. The approach is drug-free and aims to reduce complications after surgery.

This study tested whether a PET scan using a tracer called 18F-FAZA can measure low oxygen levels (hypoxia) in pancreatic cancer. Hypoxia can affect how the cancer grows and responds to treatment. 48 adults with pancreatic cancer received the scan, and researchers also collected …

This completed study tested how accurately a new pulse oximeter (a device that clips onto a finger to measure blood oxygen) works in healthy volunteers whose oxygen levels were temporarily lowered in a controlled setting. Researchers compared the device's readings to actual blood…

This study tested a pulse oximeter device that measures blood oxygen and pulse rate without needles. Eleven healthy volunteers had their oxygen levels temporarily lowered in a controlled way to see how accurate the device was compared to blood samples. The goal was to check if th…

This study tested how accurately a new pulse oximeter (a device that shines light through the skin to measure blood oxygen) works in 13 healthy adults whose oxygen levels were temporarily lowered. The device's readings were compared to actual blood samples and heart monitors. The…

This study looked at 102 children who had surgery for a heart problem present at birth. After surgery, they were placed on their stomachs with their heads raised at different angles (10°, 30°, or 45°) to see which angle best helped their heart and lungs recover. The goal was to f…

This study tested two different methods of removing the breathing tube after a C-section under general anesthesia. 120 women took part to see which method helps keep oxygen levels stable. The goal is to reduce breathing problems right after surgery.

This completed study tested how accurately new pulse oximeters measure oxygen levels and heart rate in healthy adults. Researchers lowered oxygen levels in 28 volunteers to check the devices' performance in the 60-80% range. The goal was to see if the devices meet strict accuracy…

This study checked how well a new pulse oximeter measures oxygen levels and heart rate in 30 healthy adults. Participants had their oxygen levels temporarily lowered while the device was tested during both rest and movement. The goal was to see if the device is accurate enough fo…

This completed study tested a new pulse oximetry device in 28 healthy adults aged 18 to 50. Participants had their oxygen levels temporarily lowered to check if the device accurately measures oxygen saturation (70-100%) and pulse rate (20-250 BPM). The goal was to verify the devi…

This study looked at how breathing air with more or less oxygen than normal during high-intensity interval training (Tabata) affects fitness. 23 healthy men did 9 sessions over 3 weeks on a bike while breathing either oxygen-rich or oxygen-poor air. Researchers measured changes i…

This study looked at 165 trauma patients to see how often they had low blood oxygen (hypoxemia) during their first 24 hours in the hospital. Researchers used a special finger clip to track oxygen levels and compared daytime vs. nighttime episodes. The goal was to understand when …

This study looked at whether wearing FFP2/N95 masks changes oxygen levels and pulse rate in dental professionals. Sixty dental workers took part, and researchers measured oxygen saturation and pulse while they wore the masks. The goal was to understand any short-term effects on b…

This completed study with 15 healthy volunteers tested how breathing low-oxygen and high-carbon-dioxide gas mixtures for six minutes changes heart function and blood flow. Researchers measured cardiac output and perfusion index under three conditions: low oxygen alone, high carbo…

This study compared blood oxygen readings from three different smartwatch models against a standard medical pulse oximeter. Eighteen healthy adults breathed low-oxygen mixtures to simulate hypoxia while wearing a smartwatch and a reference oximeter. The goal was to see how well t…

This study looked at whether the finger you put a pulse oximeter on affects the oxygen reading. 24 healthy adults had their oxygen levels measured during short-term low oxygen and high carbon dioxide conditions. The goal was to see if choosing a specific finger could make reading…

This completed study looked at whether a new monitoring tool called Oxygen Reserve Index (ORi) can give earlier warning of low oxygen levels in patients having varicose vein surgery under spinal anesthesia. The study included 56 adults and compared standard oxygen monitoring with…

This study tests a motorized tilt table and lower-body pressure chamber designed to help military pilots train for and understand fainting and blood pooling. Forty-six pilots and cadets will be tilted and exposed to pressure changes while their heart rate, blood pressure, and bra…

This study looked at how being at a real high altitude (3,000 meters in a mountain hut) compares to a machine that mimics low-oxygen conditions. Twenty healthy adults took part, and researchers measured things like brain oxygen, blood oxygen, heart rate, sleep quality, and altitu…

This study looked at how low oxygen levels (hypoxia) in people with obstructive sleep apnea affect the body's ability to use insulin. Researchers measured insulin resistance in the liver and fat tissue of 48 non-diabetic adults. The goal was to understand why some sleep apnea pat…

This study looked at how well smartphone apps and a special ring (Belun Ring) can measure sleep quality in adults getting braces or other orthodontic treatment. 52 people from Case Western Reserve University's dental clinic took part. They answered sleep questionnaires and used t…

This study looked at how muscle stem cells (satellite cells) respond to a single session of eccentric leg exercise in healthy young men. Participants exercised in either normal air, a low-oxygen room, or with a blood-flow restriction cuff. Muscle biopsies and blood samples were t…

This study looked at how the brain responds when people exercise while breathing low-oxygen air (like at high altitude). Thirty healthy men did exercise tests while researchers measured brain and muscle activity using special scans and stimulation. The goal was to understand why …

This study looked at whether using a continuous integrated pulmonary index (IPI) monitor can reduce the risk of low oxygen levels in older adults (65+) during painless colonoscopy. 153 participants were monitored either with or without the IPI device, which tracks breathing and h…

This completed early-phase study at the University of Missouri looked at how low oxygen (hypoxia) changes blood flow in 31 healthy adults. Researchers gave participants either a beta-blocker (propranolol) or a placebo to see if the nervous system plays a role in sex-related diffe…

This study checked how well a pulse oximeter (a device that shines light through the skin to measure blood oxygen) works when people are moving and have very low oxygen levels. Five healthy adults had their oxygen levels temporarily lowered while using the device. The goal was to…

This study checked how accurately a simple finger clip (pulse oximeter) measures oxygen levels compared to a blood test in 152 ICU patients getting extra oxygen. Researchers wanted to see if the non-invasive device matches the more precise blood gas analysis. The results could he…

This study checked how well a specific pulse oximeter (a device that clips onto a finger to measure blood oxygen) works in healthy volunteers whose oxygen levels were deliberately lowered to very low levels. Eleven adults took part. The goal was to see if the device's readings ma…

This study looked at how sleep apnea and low oxygen levels affect muscle strength and breathing in people with chronic spinal cord injury. Thirty adults with neck-level spinal cord injuries were tested using hand grip strength and muscle activity measurements. The goal was to und…