Study reveals sex differences in blood flow under low oxygen

NCT ID NCT05256069

Completed Knowledge-focused Sponsor: University of Missouri-Columbia Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed early-phase study at the University of Missouri looked at how low oxygen (hypoxia) changes blood flow in 31 healthy adults. Researchers gave participants either a beta-blocker (propranolol) or a placebo to see if the nervous system plays a role in sex-related differences. The goal is to better understand basic body responses, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propranolol pill
What this could lead to: If successful, this could help explain why men and women respond differently to low oxygen conditions, potentially guiding future treatments for blood flow problems.
What could go wrong: This is a very early, small study (31 healthy people) that only looks at short-term effects. It may not apply to people with health conditions or predict long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Aneurysm Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOXIA VASODILATION

Contacts and locations

Locations

University of Missouri-Columbia

Columbia, Missouri, 65211, United States

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