Scientists probe blood vessel changes in menopause

NCT ID NCT06417177

Recruiting now Knowledge-focused Sponsor: University of Missouri-Columbia Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study examines how aging and menopause change the way blood vessels widen in response to low oxygen. Researchers will give healthy women either a placebo, a beta-blocker (propranolol), or a bladder medication (gemtesa) to see how these drugs affect blood flow in the forearm. The goal is to better understand the role of certain receptors in blood vessel function across different stages of menopause.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propranolol and Gemtesa (oral drugs) and placebo
What this could lead to: If successful, this could help scientists understand why blood vessels react differently to low oxygen as women age and go through menopause.
What could go wrong: This is a very early phase 1 study with only 75 participants. It is designed to gather knowledge, not to test a treatment, so there may be no direct benefit to participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AGING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Aneurysm Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING HYPOXIA MENOPAUSE VASODILATION

Contacts and locations

Locations

University of Missouri-Columbia
RECRUITING

Columbia, Missouri, 65211, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.