Could a simple pacemaker setting ease right heart failure?

NCT ID NCT07470047

Not yet recruiting Disease control Sponsor: Shanghai Zhongshan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether setting a pacemaker to a faster rate (90 beats per minute) can help people with right heart failure and severe tricuspid regurgitation. Twenty-four participants with a low resting heart rate will get a special pacemaker implant and be followed for 6 months. The goal is to see if the faster pacing improves heart function, symptoms, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: permanent pacemaker implantation using left bundle branch pacing, set to 90 bpm
What this could lead to: If it works, this could offer a new way to manage right heart failure by simply adjusting heart rate with a pacemaker, potentially improving daily life and reducing symptoms.
What could go wrong: This is a very small, early-stage trial with only 24 people, so results may not apply to everyone. The faster pacing might not be tolerated or could cause side effects like discomfort or arrhythmias.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RIGHT HEART FAILURE

Contacts and locations

Locations

Shanghai Geriatric Medical Center

Shanghai, Shanghai Municipality, 201104, China
Shanghai Zhongshan Hospital

Shanghai, Shanghai Municipality, 200032, China
The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330006, China

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