New test could spot liver trouble early in fontan patients

NCT ID NCT07009132

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing a new way to measure liver function in adults who have had the Fontan procedure, a surgery for certain heart defects. Researchers will use a dual cholate clearance test (a special blood test) and a heart MRI to see how well the liver is working. They will compare results from Fontan patients, people with right heart failure, and healthy volunteers, then follow everyone for 5 years to see if the test can predict future health problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could provide a new, non-invasive way to monitor liver health in Fontan patients and predict future heart or liver problems.

What could go wrong

This is an early observational study, not a treatment trial. The test may not prove accurate or useful for predicting outcomes in this specific population.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cor pulmonale Fontan-associated liver disease heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact